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Lack of effect of gemifloxacin on the steady-state pharmacodynamics of warfarin in healthy volunteers.

Author: BirdN, DavyM, FuderH, RostK L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Gemifloxacin does not affect the pharmacodynamic effects of warfarin, allowing for safe co-administration without dose adjustments.
Paper Details　
Original Abstract of the Article :
Gemifloxacin is a novel fluoroquinolone with a broad spectrum of activity. This double-blind, randomized, parallel-group study was designed to demonstrate the lack of effect of steady-state concentrations of gemifloxacin on the pharmacodynamic effects of warfarin. Healthy male subjects received load...See full text at original site
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引用元：
https://doi.org/10.1159/000007243

データ提供：米国国立医学図書館（NLM）

Gemifloxacin and Warfarin: A Safe Passage Through the Desert of Drug Interactions

This research explores the intricate landscape of drug interactions, a critical aspect of medication safety. The authors conducted a study to investigate the potential interaction between gemifloxacin, a fluoroquinolone antibiotic, and warfarin, a blood thinner. It's like navigating a desert of potential drug interactions, ensuring a safe passage for those taking multiple medications.

A Safe Oasis: No Significant Interaction Found

The study revealed that gemifloxacin did not significantly affect the pharmacodynamic effects of warfarin. This finding suggests that these two medications can be co-administered safely without dose adjustments. It's like finding a safe oasis in the desert of drug interactions, allowing for a seamless and secure journey for those taking both medications.

Navigating the Desert of Medications: Seeking Expert Guidance

This research highlights the importance of consulting with healthcare professionals regarding potential drug interactions. It emphasizes the need for vigilance and careful monitoring when taking multiple medications. It's like having a knowledgeable guide for navigating the desert of medications, ensuring a safe and effective journey.

Dr. Camel's Conclusion

This study offers a valuable insight into the safety of co-administering gemifloxacin and warfarin. It underscores the importance of seeking expert guidance and carefully considering potential drug interactions when managing multiple medications.

Date :
  1. Date Completed 2000-05-04
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

10567780

DOI: Digital Object Identifier

10.1159/000007243

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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