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Efficacy and tolerance of three different calcium acetate formulations in hemodialysis patients.

Author: BöttgerW M, GelensM A, KaufmannB G, KlaassenH A, VerstappenV M, van den BerghJ P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated two new formulations of calcium acetate (CaAc), a phosphate binder used in patients with chronic renal failure. Neutral-coated and enteric-coated CaAc formulations were developed to address gastrointestinal discomfort, a common side effect of CaAc.
Paper Details　
Original Abstract of the Article :
Calcium acetate (CaAc) is an effective phosphate binder in patients with chronic renal failure. However, an important side effect is gastro-intestinal discomfort. Phos-ex (Cablon, The Netherlands) is the only commercially available non-coated CaAc formulation in our country. We developed two new CaA...See full text at original site
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引用元：
https://doi.org/10.1016/s0300-2977(99)00084-4

データ提供：米国国立医学図書館（NLM）

Calcium Acetate: A Desert Oasis for Phosphate Binding

The desert of chronic kidney disease can be a harsh and unforgiving landscape, with phosphate accumulation posing a significant challenge for patients. This research, like a skilled desert guide, explores the potential of calcium acetate (CaAc) as a valuable tool for managing phosphate levels in hemodialysis patients.

The researchers, like meticulous explorers, investigated the efficacy and tolerability of three different CaAc formulations, seeking a solution to the gastrointestinal discomfort often associated with this treatment. Their findings, like a well-placed oasis in the desert of phosphate management, highlight the potential benefits of CaAc while acknowledging the importance of optimizing its delivery for improved patient comfort.

A Beacon of Hope for Phosphate Management

This research, like a beacon illuminating a dark desert, offers a glimmer of hope for individuals battling chronic kidney disease. The study underscores the efficacy of CaAc in binding phosphate, a crucial step in managing this debilitating condition. This finding, like a well-worn path leading to an oasis, provides a potential avenue for improving the quality of life for patients on hemodialysis.

Navigating the Desert of Chronic Kidney Disease

The desert of chronic kidney disease is a landscape fraught with challenges. This research, like a skilled desert guide, offers valuable insights into the potential of CaAc for managing phosphate levels. While further research is needed to optimize its delivery and minimize side effects, this study underscores the importance of exploring new and innovative therapies to combat this challenging condition.

Dr. Camel's Conclusion

This research, like a refreshing oasis in a parched landscape, offers a glimmer of hope for individuals battling chronic kidney disease. While the journey to optimize CaAc delivery and minimize side effects is ongoing, this study underscores the importance of continued exploration and the pursuit of new and innovative therapies to combat this challenging condition.

Date :
  1. Date Completed 1999-12-30
  2. Date Revised 2019-11-03
Further Info :

Pubmed ID

10593132

DOI: Digital Object Identifier

10.1016/s0300-2977(99)00084-4

Related Literature

Article Analysis
・Side Effects of calcium acetate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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