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[Role of suindac in the treatment of familial adenomatous polyposis coli].

Author: BergmannJ F, CaulinC, HalimiC, LandauerS

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Sulindac is an effective treatment for colorectal adenomatous polyps in patients with familial adenomatous polyposis. However, it does not affect other manifestations of the disease and polyps may recur after cessation of therapy. Total colectomy is the recommended procedure for most patients with familial adenomatous polyposis.
Paper Details　
Original Abstract of the Article :
Familial adenomatous polyposis is a rare genetic disease characterized by the development of colorectal adenomatous polyps. Extracolonic digestive and extra-digestive manifestations can also appear. Inevitably, colorectal cancer occurs if a colectomy is not performed. Sulindac is an indolic non-ster...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/10709439

データ提供：米国国立医学図書館（NLM）

Navigating the Shifting Sands of Familial Adenomatous Polyposis: The Role of Sulindac

The world of genetic disorders presents unique challenges, and Familial Adenomatous Polyposis (FAP) is no exception. This study investigates the potential role of sulindac, a non-steroidal anti-inflammatory drug (NSAID), in the management of FAP. The authors review the literature on sulindac's impact on FAP, focusing on its ability to decrease colonic tumoral proliferation and potentially prevent the development of colorectal cancer. The study highlights the benefits of sulindac in reducing polyp size and number, but also underscores the need for ongoing treatment and careful monitoring due to the potential for relapse and side effects.

Navigating the Shifting Sands of Familial Adenomatous Polyposis: The Role of Sulindac

This review highlights the potential of sulindac as a therapeutic tool for managing FAP. The authors emphasize the need for careful consideration of the risks and benefits associated with this medication, and they recommend a personalized approach to treatment based on individual patient characteristics and preferences.

Navigating the Shifting Sands of Familial Adenomatous Polyposis: The Role of Sulindac

For individuals diagnosed with FAP, open communication with your healthcare provider is vital. Discuss all treatment options, including surgery, medication, and lifestyle modifications, to develop a comprehensive management plan that addresses your specific needs and concerns.

Dr. Camel's Conclusion

FAP presents a unique challenge, requiring a multi-faceted approach to management. Sulindac offers a promising tool in this journey, but careful consideration of its risks and benefits is essential. Remember, navigating the shifting sands of FAP requires a collaborative effort between patients and healthcare providers, working together to achieve optimal health outcomes.

Date :
  1. Date Completed 2000-04-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10709439

DOI: Digital Object Identifier

10709439

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in preparation
Languages

French

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