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Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Author: MillerR G, MitchellJ D, MooreD H
Original Abstract of the Article :
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis (ALS) in some countries but not others. Questions persist about its clinical utility because of high cost, modest efficacy and concern over adverse effects. OBJECTIVES: To examine the efficacy of ril...See full text at original site
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/14651858.CD001447
データ提供:米国国立医学図書館(NLM)
Riluzole: A Hopeful Light in the Darkness of ALS
Amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, is a formidable foe for researchers and clinicians. While there is no cure for ALS, the search for effective treatments continues. This study examines the efficacy of riluzole, a medication approved in some countries for the treatment of ALS. The researchers conducted a systematic review of randomized controlled trials to assess the effects of riluzole on survival and the use of life-sustaining interventions, such as tracheostomy and mechanical ventilation.
The findings revealed that riluzole, specifically at a dose of 100 mg per day, modestly prolonged survival in patients with ALS. The study also showed that riluzole delayed the need for life-sustaining interventions, providing a critical window for improved quality of life and autonomy for patients. These results demonstrate the potential benefits of riluzole in managing ALS, offering a glimmer of hope for patients and their families.
Riluzole: A Modest Victory in the Fight Against ALS
The study’s findings, while modest, are significant in the context of ALS, a disease with limited treatment options. Riluzole’s ability to prolong survival and delay the need for life-sustaining interventions is a valuable contribution to the management of this devastating disease. Further research is needed to optimize the use of riluzole and explore new therapeutic strategies for ALS.
Riluzole: A Beacon of Hope for ALS Patients
For individuals diagnosed with ALS, every day counts. Riluzole offers a ray of hope, providing a chance to extend life and maintain a better quality of life for a longer period. It’s important to remember that riluzole is not a cure for ALS, but it can be a valuable tool in managing the disease and improving the lives of patients.
Dr.Camel's Conclusion
The desert of ALS can feel vast and unforgiving, but riluzole offers a small oasis of hope. While this medication doesn’t conquer the disease, it provides a chance to extend life and improve quality of life. This study reminds us of the importance of relentless research and the ongoing search for effective treatments for debilitating diseases.
Date :
- Date Completed 2000-07-06
- Date Revised 2018-12-21
Further Info :
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