World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Task Force on Post-Ovulatory Methods of Fertility Regulation. vonhertzenh@who.ch.

Author:

Overview

Levonorgestrel 0.75 mg administered immediately after intercourse is not suitable for regular postcoital contraception. The Pearl index failure rate was 6.8 pregnancies per 100 woman-years of use. One-third of participants discontinued the study within 6 months due to bleeding problems. Menstrual complaints were reported by 70% of women. Other common complaints included nausea, breast tenderness, weakness, dizziness, headache, and abdominal bloating.

Paper Details　

Original Abstract of the Article :

We evaluated the efficacy and side effects of immediate postcoital administration of levonorgestrel 0.75 mg used repeatedly for contraception. A total of 295 healthy women with infrequent coitus were enrolled at 6 study sites. Each woman took levonorgestrel 0.75 mg by mouth immediately after interco...See full text at original site

Dr.Camel's Paper Summary Blog

Levonorgestrel for Postcoital Contraception: A Desert of Contraception

Contraception is a crucial aspect of reproductive health, providing individuals with the ability to plan and control their families. This study evaluates the efficacy and side effects of immediate postcoital levonorgestrel for repeated contraception. It's like navigating a desert of contraception, seeking effective and safe options to prevent unintended pregnancies.

The study found that levonorgestrel pills were effective in preventing pregnancy but had a high rate of discontinuation due to side effects, particularly menstrual irregularities. It's like trying to find a sustainable water source in a desert, only to discover that it comes with a high price, both in terms of side effects and potential drawbacks.

A Desert of Side Effects

The study reveals that while levonorgestrel pills can be effective, they are not suitable for regular postcoital contraception due to their high rate of side effects. It's like discovering a hidden oasis in the desert, only to find that it is inhabited by venomous snakes and other hazards.

Exploring Other Options

This study emphasizes the need for exploring other contraceptive options that are both effective and well-tolerated. It's like searching for a safe and reliable path through the desert, avoiding treacherous landscapes and seeking a more sustainable journey.

Dr.Camel's Conclusion

This study provides valuable insights into the challenges associated with postcoital contraception, highlighting the need for further research and development of safe and effective contraceptive options. It's like recognizing that the desert of contraception is vast and complex, requiring careful exploration and innovation to find the best paths for individuals to navigate.