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The side effects burden of extended imipramine treatment of panic disorder.

Author: MavissakalianM R, PerelJ M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Imipramine, a tricyclic antidepressant, was found to be effective in treating panic disorder with agoraphobia in a study of 110 patients. While the drug caused some side effects, such as dry mouth, sweating, and constipation, these side effects generally improved over time.
Paper Details　
Original Abstract of the Article :
In a recent study, the authors gauged the net effectiveness of imipramine to be 53%; that is, of 110 patients having panic disorder with agoraphobia who started a course of imipramine at a fixed, targeted, weight-adjusted dose of 2.25 mg x kg(-1) x day(-1), 59 adhered to the regimen and showed a mar...See full text at original site
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引用元：
https://doi.org/10.1097/00004714-200010000-00010

データ提供：米国国立医学図書館（NLM）

Long-Term Imipramine Treatment for Panic Disorder: Assessing Side Effects

Panic disorder, a common anxiety disorder, can be debilitating. This study, published in the Journal of Clinical Psychiatry, investigated the side effects associated with extended imipramine treatment for panic disorder. The researchers examined the side effects experienced by patients over a 6-month period.

Managing Side Effects of Imipramine Treatment

The study found that while some side effects, such as dry mouth, sweating, and constipation, persisted over the course of treatment, most side effects decreased or disappeared. The researchers also observed a sustained increase in heart rate but no significant effects on blood pressure or weight.

Balancing Benefits and Risks of Imipramine

This study provides valuable information for clinicians and patients considering imipramine treatment for panic disorder. It emphasizes the importance of carefully monitoring side effects and weighing the potential benefits of treatment against potential risks.

Dr.Camel's Conclusion

Navigating panic disorder is like traversing a desert of anxiety, with fears and worries looming large. This study provides insights into the side effects associated with imipramine treatment, highlighting the need for careful consideration of both benefits and risks. As with any journey through the desert, understanding the potential challenges and finding the right tools can lead to a smoother and more successful path towards recovery.
Date :
  1. Date Completed 2001-02-02
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

11001240

DOI: Digital Object Identifier

10.1097/00004714-200010000-00010

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・Side Effects of imipramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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