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Serious side effects of rifampin on the course of WHO/MDT: a case report.

Author: NamisatoM, OgawaH

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A patient with leprosy experienced a severe reaction to rifampin (RMP) after 3 doses of monthly RMP. The reaction included flu-like symptoms, shock, intravascular hemolysis, and acute renal failure. This case highlights the potential for serious adverse effects from RMP, especially in patients with prior RMP exposure or multibacillary leprosy.
Paper Details　
Original Abstract of the Article :
A male born in 1935 was diagnosed as having lepromatous leprosy when he was 17 years old. In addition to dapsone (DDS) monotherapy, he had been treated with rifampin (RMP) for 2 terms: first with 450 mg a day for 2 years when he was 39 years old; second with 150 mg a day for 2 months after a 1-year ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11221090

データ提供：米国国立医学図書館（NLM）

Rifampin: A Double-Edged Sword in the Fight Against Leprosy

Leprosy, a chronic infectious disease caused by the bacterium Mycobacterium leprae, has plagued humanity for centuries. Imagine leprosy as a persistent desert storm, leaving its mark on those affected. This case report examines the serious side effects of rifampin, a powerful antibiotic used to treat leprosy, highlighting the potential risks associated with this treatment. Rifampin is like a double-edged sword, offering the promise of healing but also carrying the potential for harm.

The Storm's Aftermath: The Potential Dangers of Rifampin

The case report describes a patient who experienced severe adverse effects after receiving rifampin, including a flu-like syndrome, shock, hemolysis, and acute renal failure. This case highlights the importance of monitoring patients closely for potential side effects and underscores the need for caution when using rifampin, especially in patients with a history of prior treatment with this drug. This research reminds us that even in the fight against disease, we must be aware of the potential risks and carefully weigh the benefits against the dangers.

Navigating the Desert of Leprosy Treatment

This case report emphasizes the importance of patient safety and the need for individualized care in the treatment of leprosy. It highlights the need for close monitoring and careful consideration of individual risk factors when prescribing rifampin. Just as a desert traveler needs to be aware of the potential hazards, healthcare providers must be vigilant in managing the risks associated with this powerful antibiotic.

Dr. Camel's Conclusion

This case report serves as a reminder that even in the fight against serious diseases, we must proceed with caution and consider all potential risks. It underscores the importance of patient monitoring and individualized care, ensuring that the benefits of treatment outweigh the potential dangers.
Date :
  1. Date Completed 2001-03-08
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

11221090

DOI: Digital Object Identifier

11221090

Related Literature

Article Analysis
・Side Effects of rifampin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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