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A framework for evaluating the clinical consequences of initial therapy with NSAIDs, NSAIDs plus gastroprotective agents, or celecoxib in the treatment of arthritis.

Author: BurkeT A, GoldsteinJ L, ManiadakisN, MaurathC J, PettittD, ZabinskiR A

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study aims to compare the economic efficiency of NSAIDs, gastroprotective agents, and celecoxib for treating osteoarthritis and rheumatoid arthritis.
Paper Details　
Original Abstract of the Article :
The purpose of this study is to provide a framework for estimating the economic efficiency of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs), concomitant gastroprotective agents (GPAs) to reduce the risk of NSAID toxicity, and celecoxib, a specific cyclo-oxygenase-2 inhibitor. Concomitan...See full text at original site
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引用元：
https://doi.org/10.2165/00019053-200119001-00003

データ提供：米国国立医学図書館（NLM）

Evaluating NSAID Therapy for Arthritis

This study tackles a critical issue in the management of arthritis – the balance between pain relief and potential gastrointestinal side effects. The authors propose a framework for evaluating the cost-effectiveness of different NSAID therapies, considering both the effectiveness in reducing pain and the risk of gastrointestinal complications. The study delves into various approaches, including the use of gastroprotective agents alongside NSAIDs and the use of celecoxib, a specific cyclo-oxygenase-2 inhibitor.

The Economics of Arthritis Treatment

The study emphasizes the need for a comprehensive approach to evaluating NSAID therapy, considering both clinical benefits and potential costs. By comparing different therapeutic strategies, including the use of gastroprotective agents, the authors aim to identify the most efficient and cost-effective treatment options for managing arthritis.

Navigating the Desert of NSAID Therapy

Choosing the right NSAID therapy for arthritis can be like navigating a vast desert – a challenging landscape where finding the right path is essential. This study provides a roadmap, helping us to understand the trade-offs between pain relief and potential gastrointestinal side effects, ultimately leading to a more informed and personalized approach to treating arthritis.

Dr.Camel's Conclusion

Like the shifting sands of a desert, NSAID therapy for arthritis requires careful consideration of various factors. This study provides a framework for evaluating the different options, helping physicians and patients make informed decisions that balance pain relief and minimize potential risks.

Date :
  1. Date Completed 2001-04-12
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

11280104

DOI: Digital Object Identifier

10.2165/00019053-200119001-00003

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Languages

English

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