Paper Details

  1. Home
  2. Paper Details

The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product.

Author: HickmanJ G, JarrattM T, LevyS F, LeydenJ J, StewartD M

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Benzoyl peroxide/clindamycin demonstrated improved efficacy and similar tolerability compared to benzoyl peroxide used alone and was similar to benzoyl peroxide/erythromycin, making this combination product an effective alternative antimicrobial therapy for acne.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Topical clindamycin and benzoyl peroxide have each demonstrated clinical efficacy in the treatment of acne vulgaris. When used in tandem, they promise greater efficacy than either individual agent through their antibacterial and anti-inflammatory effects. OBJECTIVE: To determine the eff...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1177/120347540100500109

データ提供：米国国立医学図書館（NLM）

The Efficacy and Safety of Combination Benzoyl Peroxide/Clindamycin Gel for Acne

This study dives deep into the [dermatology] field by investigating the efficacy and safety of a combination benzoyl peroxide/clindamycin gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product. This study, with its meticulous design and thorough analysis, aims to determine the optimal topical treatment for acne vulgaris, a common skin condition.

Benzoyl Peroxide/Clindamycin: A Promising Acne Treatment

The study demonstrates that the combination of benzoyl peroxide/clindamycin significantly outperforms benzoyl peroxide alone in reducing inflammatory acne lesions and achieving overall improvement. This finding suggests that the synergistic effects of these two agents could be a more effective approach for treating acne compared to using either agent alone. The study also indicates that benzoyl peroxide/clindamycin exhibits similar efficacy and tolerability as benzoyl peroxide/erythromycin, making it a valuable alternative treatment option.

Managing Acne: Understanding the Role of Combination Therapies

This research underscores the importance of considering combination therapies in managing acne. The findings highlight the potential benefits of combining benzoyl peroxide with an antibiotic like clindamycin, suggesting that this approach may offer a more effective and well-tolerated treatment option for patients with acne vulgaris.

Dr.Camel's Conclusion

This research, like a camel traversing the vast desert of dermatology, investigates the efficacy and safety of different topical treatments for acne. The findings suggest that a combination of benzoyl peroxide and clindamycin may offer a more effective and well-tolerated approach compared to using either agent alone. This study acts as a guidepost, leading us toward a better understanding of acne treatment options and empowering clinicians to make informed decisions about patient care.

Date :
  1. Date Completed 2001-06-14
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

11281433

DOI: Digital Object Identifier

10.1177/120347540100500109

Related Literature

Article Analysis
・Effects of clindamycin topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.