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Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial.

Author: Ahmadi-AbhariS A, AkhondzadehS, AssadiS M, FarzanehganZ M, KamlipourA, ShabestariO L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Baclofen was found to be at least as effective as clonidine in managing physical symptoms of opiate withdrawal syndromes and superior to clonidine in managing mental symptoms.
Paper Details　
Original Abstract of the Article :
Baclofen is known for the alleviation of signs and symptoms of spasticity. Reports from our previous study have suggested that it may be at least as effective as clonidine in the management of physical symptoms of opiate withdrawal syndromes and superior to clonidine in the management of mental symp...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2710.2001.00325.x

データ提供：米国国立医学図書館（NLM）

Baclofen versus Clonidine in the Treatment of Opiates Withdrawal: Side-Effects Aspect

Imagine a desert traveler facing the harsh realities of opioid withdrawal, a challenging and uncomfortable experience. This research explores two medications, baclofen and clonidine, both used to ease the symptoms of opioid withdrawal. It's like comparing two different approaches to navigating the desert, seeking the most effective and safe route. The researchers conducted a double-blind, randomized controlled trial to compare the effectiveness and side effects of baclofen and clonidine in managing opioid withdrawal.

Finding Relief in the Desert of Withdrawal

The study found that baclofen was at least as effective as clonidine in managing the physical symptoms of opioid withdrawal, like providing a temporary oasis from the intense heat and thirst. However, baclofen was found to be more effective in managing the mental symptoms, providing a greater sense of calm and well-being, like finding a cool spring in the midst of the scorching desert.

Navigating the Desert with Caution

This research highlights the potential of baclofen as a valuable tool for managing opioid withdrawal, offering a more comprehensive approach to this challenging experience. It's like discovering a new and reliable source of water in the desert, providing relief and hope for those struggling with addiction. However, it's essential to consult with a medical professional to determine the best treatment options and to be aware of potential side effects. Just as a desert traveler must be cautious and prepared, managing opioid withdrawal requires careful consideration and expert guidance.

Dr. Camel's Conclusion

This research compares two medications used to manage opioid withdrawal, like comparing two different paths across the desert. While both medications offer relief, baclofen appears to be more effective in managing the mental aspects of withdrawal. It's like finding a well-equipped oasis, providing a more comprehensive approach to managing the challenges of opioid withdrawal.

Date :
  1. Date Completed 2001-05-24
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

11286609

DOI: Digital Object Identifier

10.1046/j.1365-2710.2001.00325.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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