Hexamethylmelamine in ovarian cancer resistant to cyclophosphamide and adriamycin.

Author: BelloniC, BolisG, D'IncalciM, MangioniC

Paper Details 
Original Abstract of the Article :
Thirty-four patients resistant to cyclophosphamide and Adriamycin received hexamethylmelamine at one of two dose regimens: 6 mg/kg/day orally for 21 days every 4 weeks or 8 mg/kg/day orally for 21 days every 6 weeks. Only five patients responded. Tolerance to the drug was, however, satisfactory; nau...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/113096

データ提供:米国国立医学図書館(NLM)

Hexamethylmelamine: A Potential Weapon Against Resistant Ovarian Cancer

The fight against [ovarian cancer] demands innovative therapies to overcome drug resistance. This study explores the use of [hexamethylmelamine] as a treatment option for patients with [ovarian cancer] who have become resistant to standard chemotherapy drugs, such as [cyclophosphamide] and [adriamycin]. Researchers investigated the effectiveness and tolerability of [hexamethylmelamine] in this challenging patient population. Their findings suggest that [hexamethylmelamine] may offer a potential alternative for treating resistant [ovarian cancer], but its efficacy remains limited.

Hexamethylmelamine: A Hopeful but Limited Treatment Option

The study found that only a small number of patients (five out of 34) responded to [hexamethylmelamine] treatment. While the drug was generally well-tolerated, with only minimal side effects, its efficacy was limited. These findings suggest that [hexamethylmelamine] may be a potential option for some patients with resistant [ovarian cancer], but further research is needed to optimize its use and identify potential predictors of response.

Implications for Health and Lifestyle

The study emphasizes the urgent need for developing new and effective therapies for [ovarian cancer], particularly for patients who have become resistant to standard treatments. It highlights the importance of continued research to identify novel targets and strategies for combatting this devastating disease.

Dr.Camel's Conclusion

This study takes us into the challenging world of [ovarian cancer] treatment, specifically focusing on the search for effective therapies for resistant cases. While [hexamethylmelamine] shows some promise, its limited efficacy underscores the need for continued exploration of new therapeutic approaches to effectively combat this disease.

Date :
  1. Date Completed 1979-11-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

113096

DOI: Digital Object Identifier

113096

Related Literature

SNS
PICO Info
in preparation
Languages

English

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