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Incidence and clinical relevance of the interactions and side effects of Hypericum preparations.

Author: SchulzV

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
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Overview

Observational studies with preparations of St. John's wort have recorded an incidence of adverse events (AE) among those treated of between 1 and 3%. The most common adverse events (1 per 300000 treated cases) among the spontaneous reports in the official register concern reactions of the skin exposed to light. Co-medication with ciclosporin and indinavir, and for the time being, other protease inhibitors used in anti-HIV treatment, is absolutely contraindicated.
Paper Details　
Original Abstract of the Article :
Observational studies with preparations of St. John's wort have recorded an incidence of adverse events (AE) among those treated of between 1 and 3%. This is some ten times less than with synthetic antidepressants. The most common adverse events (1 per 300000 treated cases) among the spontaneous rep...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/11315759

データ提供：米国国立医学図書館（NLM）

St. John's Wort: A Natural Antidepressant with a Touch of Caution

The field of mental health is constantly exploring new avenues for treatment, and natural remedies like St. John's Wort have gained popularity. This study delves into the adverse effects and interactions associated with St. John's Wort, shedding light on its potential risks when used in conjunction with other medications. The authors found that St. John's Wort preparations have an incidence of adverse events of 1-3%, significantly lower than synthetic antidepressants. However, they identified a potential for photosensitization, a heightened sensitivity to sunlight, particularly at doses exceeding 2-4 grams per day of a typical commercial extract. The authors highlight the importance of careful monitoring when co-administering St. John's Wort with other antidepressants, anticoagulants, and certain protease inhibitors used in HIV treatment.

Navigating the Desert of Side Effects: St. John's Wort's Potential Interactions

This research highlights the importance of considering the potential interactions of natural remedies like St. John's Wort with other medications. It's like navigating a vast desert; you must carefully map out your path and be aware of the hidden dangers. While St. John's Wort might offer a natural solution for mental health, it's crucial to consult with a healthcare professional before incorporating it into your treatment plan, especially if you're taking other medications.

St. John's Wort: A Balancing Act between Benefits and Risks

St. John's Wort can provide a glimmer of hope for those seeking natural alternatives to conventional antidepressants, but it's important to remember that it's not without its potential risks. Like a delicate oasis in the desert, its benefits must be carefully balanced with the potential for side effects. Always consult with a healthcare professional to determine if St. John's Wort is right for you and to ensure safe and effective use.

Dr.Camel's Conclusion

St. John's Wort is an intriguing natural remedy, but its use requires careful consideration. It's like a camel traversing a desert; you must be aware of the hidden dangers and navigate the terrain with caution. This study reminds us that even natural remedies can have unforeseen consequences, emphasizing the importance of consulting with healthcare professionals before embarking on any new treatment plan.

Date :
  1. Date Completed 2001-09-06
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

11315759

DOI: Digital Object Identifier

11315759

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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