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Studies on the use of Yucca schidigera to control giardiosis.

Author: AnnettC B, CheekeP R, CockwillC L, McAllisterT A, OlsonM E, WangY

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Yucca schidigera powder and its butanol extract were shown to have anti-giardial activity in vitro and in vivo. The butanol extract, at concentrations of 1500 microg/ml, showed similar effects on trophozoites as metronidazole at 40 microg/ml. Oral administration of butanol extract or metronidazole reduced the number of trophozoites in the small intestine of infected gerbils. Further purification and concentration of the saponin fraction from Y. schidigera may provide more effective anti-giardial treatments.
Paper Details　
Original Abstract of the Article :
The potential anti-giardial activity of a powdered preparation of Yucca schidigera (yucca powder) was investigated in vitro, in a modified adherence inhibition assay, and in vivo, by enumeration of trophozoites (intestinal) or cysts (fecal) in experimentally infected gerbils and lambs receiving oral...See full text at original site
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引用元：
https://doi.org/10.1016/s0304-4017(01)00394-6

データ提供：米国国立医学図書館（NLM）

Yucca schidigera for Giardiosis: A Desert Oasis of Anti-Giardial Activity?

Giardiosis, a parasitic infection that causes gastrointestinal distress, is like a pesky desert creature that can disrupt the body's balance. This study, conducted like a well-planned camel caravan expedition, explored the potential anti-giardial activity of Yucca schidigera, a plant that has long been used for its medicinal properties. They conducted both in vitro and in vivo studies, testing the effects of Yucca schidigera extracts on Giardia parasites. The results were as clear as a desert sky after a sandstorm: Yucca schidigera extracts showed significant anti-giardial activity in vitro, but the in vivo results were less conclusive. While Yucca schidigera may hold promise for the treatment of giardiosis, further research is needed to fully understand its effectiveness and safety.

Yucca schidigera: A Desert Oasis with Potential

This study, as vast as the desert itself, demonstrates that Yucca schidigera extracts exhibit significant anti-giardial activity in vitro. The findings, as clear as a desert well after a long trek, provide a promising avenue for the development of new treatments for giardiosis. However, more research is needed to confirm its effectiveness and safety in humans.

Giardiosis and Yucca schidigera: Navigating the Desert Landscape

Giardiosis, a parasitic infection, can cause uncomfortable and debilitating gastrointestinal symptoms. Yucca schidigera, a plant with a long history of medicinal use, may hold potential for treating this condition. This study, like a well-marked trail in the desert, provides valuable insights into the potential benefits of Yucca schidigera for giardiosis, but further research is crucial to explore its effectiveness and safety in humans.

Dr. Camel's Conclusion

This study, conducted like a well-planned camel caravan expedition, provides promising evidence for the potential anti-giardial activity of Yucca schidigera. The findings, as clear as a desert sky after a sandstorm, suggest that Yucca schidigera may hold promise as a treatment for giardiosis, but further research is needed to confirm its effectiveness and safety in humans.
Date :
  1. Date Completed 2001-10-18
  2. Date Revised 2019-08-26
Further Info :

Pubmed ID

11358624

DOI: Digital Object Identifier

10.1016/s0304-4017(01)00394-6

Related Literature

Article Analysis
・Effective treatment of giardia infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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