The use of intravenous immunoglobulin as maintenance therapy in myasthenia gravis.

Author: ChapmanJ, DroryV E, HilkevichO, KorczynA D

Paper Details 
Original Abstract of the Article :
The standard therapy for myasthenia gravis (MG) includes steroids and immunosuppressants, which have delayed onset of action and significant side effects. Plasmapheresis and intravenous immunoglobulin have been used mostly for the treatment of severe exacerbations. In the present study we examined t...See full text at original site
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引用元:
https://doi.org/10.1097/00002826-200105000-00010

データ提供:米国国立医学図書館(NLM)

Intravenous Immunoglobulin: A Potential Solution for Myasthenia Gravis Management

Myasthenia gravis (MG) is a debilitating autoimmune disease that affects the muscles. The standard treatment, which includes steroids and immunosuppressants, can have delayed effects and significant side effects. This study explores the use of intravenous immunoglobulin (IVIg) as a maintenance therapy for MG. The researchers focused on a group of 11 patients with generalized MG, all of whom had severe symptoms, including bulbar and respiratory involvement. The study found that IVIg, given at a specific dosage, led to significant improvements in all patients. Most importantly, none of the patients required mechanical ventilation during the treatment period. Furthermore, the study found that the dosages of steroids and pyridostigmine could be reduced, and steroids were even discontinued in two patients. Overall, this study suggests that IVIg may be a valuable tool for managing MG and improving quality of life for patients.

IVIg Offers a Promising Treatment Option

This research provides evidence supporting the use of IVIg as a maintenance treatment for MG. The findings indicate that IVIg can be a safe and effective option for managing symptoms and improving patients’ quality of life. This study shows that IVIg can lead to significant improvements in MG patients, including a reduction in the need for mechanical ventilation and the ability to decrease or discontinue other medications.

Understanding the Benefits and Risks of IVIg

While IVIg shows promise as a treatment for MG, it's important to consult with a healthcare professional to understand its potential benefits and risks. IVIg can be a powerful tool, but it's crucial to use it in a way that's tailored to each individual's needs. Remember, it's always wise to seek guidance from a medical professional before making any decisions about your treatment plan.

Dr. Camel's Conclusion

This study offers hope for individuals with MG by demonstrating the potential benefits of IVIg as a maintenance treatment. While further research is needed to fully understand the long-term effects and optimal treatment strategies, IVIg appears to be a valuable option for improving symptoms and quality of life. Remember, staying informed about the latest medical advancements and discussing your treatment options with your doctor is crucial for managing MG.

Date :
  1. Date Completed 2001-10-04
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

11391130

DOI: Digital Object Identifier

10.1097/00002826-200105000-00010

Related Literature

SNS
PICO Info
in preparation
Languages

English

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