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Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.
Author: GariépyJ, LevensonJ, MoyseD, SimonA
Original Abstract of the Article :
BACKGROUND: Common carotid artery intima-media thickness (IMT) progression was compared between 4 years of treatment with nifedipine and diuretic. METHODS AND RESULTS: This study, ancillary to the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT), invol...See full text at original site
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引用元:
https://doi.org/10.1161/01.cir.103.24.2949
データ提供:米国国立医学図書館(NLM)
Nifedipine vs. Co-Amilozide: A Tale of Two Antihypertensives and Carotid Wall Changes
Hypertension, or high blood pressure, is a silent killer, often leading to serious cardiovascular complications. This study delves into the effects of two different antihypertensive treatments, nifedipine and co-amilozide, on the progression of early carotid wall changes. The study was designed as a comparative analysis, examining the long-term impact of each medication on carotid intima-media thickness (IMT), a marker of early atherosclerosis (hardening of the arteries). The results revealed distinct effects of the two treatments, highlighting the importance of individualized approaches to hypertension management.
Nifedipine: A Gentle Touch on Carotid Walls
The study found that nifedipine had no significant effect on the progression of carotid wall changes. In contrast, co-amilozide was associated with increased IMT progression, suggesting a potential negative impact on arterial health. It's like comparing two camels who are trying to cross a desert – one camel walks gracefully, leaving no trace, while the other disturbs the fragile sand dunes with each step.
Choosing the Right Antihypertensive: A Balancing Act
The study emphasizes the importance of considering the potential long-term effects of different antihypertensive medications on cardiovascular health. While both nifedipine and co-amilozide effectively lower blood pressure, the study suggests that nifedipine may offer a more favorable profile in terms of its impact on arterial health. It's like choosing the right camel for a long journey – a camel with a gentle gait may be more suitable for navigating delicate terrain.
Dr.Camel's Conclusion
This study provides valuable insights into the differential effects of nifedipine and co-amilozide on carotid wall changes. It underscores the importance of considering the long-term implications of antihypertensive treatment choices, highlighting the need for personalized approaches to hypertension management. It’s like a camel trekking through the desert – each camel has its own strengths and weaknesses, and choosing the right one for the journey is crucial.
Date :
- Date Completed 2001-07-19
- Date Revised 2019-06-23
Further Info :
Related Literature
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