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The impact of docetaxel, estramustine, and low dose hydrocortisone on the quality of life of men with hormone refractory prostate cancer and their partners: a feasibility study.

Author: , GodleyP A, HerndonJ E, KornblithA B, SavareseD, VogelzangN J, ZuckermanE

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study assessed the quality of life (QoL) of men with hormone-refractory prostate cancer (HRPC) and their partners in a multicenter Phase II trial.
Paper Details　
Original Abstract of the Article :
The quality of life (QoL) of 44 men with HRPC and 37 partners (primary caregivers, most residing with the patient) was assessed in a multicenter Phase II trial of docetaxel, estramustine and low dose hydrocortisone (CALGB 9780). A secondary objective was to test the feasibility of assessing partners...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11432621

データ提供：米国国立医学図書館（NLM）

Quality of Life in Men with Prostate Cancer: A Focus on Treatment

The diagnosis of [hormone refractory prostate cancer (HRPC)] can be a daunting experience, like navigating a vast and unforgiving desert. This research explores the impact of [docetaxel, estramustine, and low dose hydrocortisone] on the quality of life of men with [HRPC]. The authors use a [multicenter Phase II trial] to evaluate the [feasibility and impact] of these treatments on [patients and their partners]. The study highlights the importance of considering the [impact of treatment] on both [patients and caregivers] to improve overall well-being.

The Journey Through Treatment: Understanding the Impact on Quality of Life

The authors' findings underscore the importance of [considering the impact of treatment] on both [patients and their partners] when managing [HRPC]. They demonstrate that [treatment] can have a significant impact on [quality of life], both for the patient and their loved ones. It's like understanding the intricate balance of a desert ecosystem, where the well-being of one organism is intertwined with the well-being of others.

Navigating the Desert of Prostate Cancer: Support and Resources for Patients and Caregivers

This research highlights the need for [comprehensive care] that addresses the [physical and emotional] needs of both [patients and caregivers] throughout the [treatment journey]. It's important to [seek support] from [healthcare professionals, support groups, and loved ones] to navigate the challenges of [HRPC]. Remember, you are not alone in this journey. There are resources available to help you through every step of the way.

Dr.Camel's Conclusion

This research is a reminder that [prostate cancer] is not just a physical disease, but also a [social and emotional] one. It highlights the importance of [considering the needs of both patients and their caregivers] when developing treatment plans. It's like seeking a hidden oasis in the desert - you need to look beyond the immediate landscape and understand the interconnectedness of the entire ecosystem to find true well-being.

Date :
  1. Date Completed 2001-12-04
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

11432621

DOI: Digital Object Identifier

S0923-7534(19)54116-3

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Article Analysis
・Side Effects of estramustine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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