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A randomized trial of lansoprazole, amoxycillin, and clarithromycin versus lansoprazole, bismuth, metronidazole and tetracycline in the retreatment of patients failing initial Helicobacter pylori therapy.
Author: BurmM, FaigelD, FennertyM B, KellyC, MagaretN, PetersonW
Original Abstract of the Article :
10-30% of the patients treated for Helicobacter pylori fail to clear the infection after initial therapy. Little is known as to the efficacy of retreatment regimens in these patients. Proton pump inhibitor (PPI) -based triple and quadruple therapies demonstrate efficacies of 80-90% as initial therap...See full text at original site
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引用元:
https://doi.org/10.1159/000050674
データ提供:米国国立医学図書館(NLM)
Retreatment of Helicobacter pylori Infection: Lansoprazole, Amoxycillin, and Clarithromycin vs. Lansoprazole, Bismuth, Metronidazole, and Tetracycline
This randomized trial investigates the efficacy of two different treatment regimens for [Helicobacter pylori] infection in patients who failed initial therapy. The study compared the effectiveness of a [nonmetronidazole-containing PPI-based triple therapy] to a [PPI-based quadruple therapy containing metronidazole]. The findings suggest that both regimens have comparable efficacy in eradicating [Helicobacter pylori] in patients who failed initial therapy, offering clinicians valuable insights into alternative treatment options for this challenging condition.
Effective Strategies for Retreatment of Helicobacter pylori Infection
The study's findings provide valuable guidance for clinicians in managing [Helicobacter pylori] infection, particularly in patients who have failed initial therapy. The research suggests that both [nonmetronidazole-containing PPI-based triple therapy] and [PPI-based quadruple therapy containing metronidazole] are effective in eradicating [Helicobacter pylori] infection, offering alternative treatment options to clinicians.
Improving Patient Outcomes in Helicobacter pylori Management
The study's findings underscore the importance of having effective treatment options for [Helicobacter pylori] infection, particularly in patients who fail initial therapy. The research suggests that both [nonmetronidazole-containing PPI-based triple therapy] and [PPI-based quadruple therapy containing metronidazole] offer viable alternatives, potentially improving patient outcomes and minimizing the risk of treatment failure.
Dr. Camel's Conclusion
This randomized trial provides valuable insights into the efficacy of different treatment regimens for [Helicobacter pylori] infection in patients who have failed initial therapy. The findings suggest that both [nonmetronidazole-containing PPI-based triple therapy] and [PPI-based quadruple therapy containing metronidazole] offer viable alternatives, expanding the options available to clinicians for managing this challenging condition.
Date :
- Date Completed 2001-10-18
- Date Revised 2017-11-01
Further Info :
Related Literature
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