ACTH therapy of West syndrome: Finnish views.

Author: RiikonenR

Paper Details 
Original Abstract of the Article :
To provide up-to-date information on adrenocorticotropic hormone (ACTH) therapy in the treatment of West syndrome, a review of the Finnish studies was made in answer to the questions: what are (1) its efficacy: doses and comparison with vigabatrin (VGB), (2) its tolerability, (3) its mechanism of ac...See full text at original site
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引用元:
https://doi.org/10.1016/s0387-7604(01)00306-0

データ提供:米国国立医学図書館(NLM)

ACTH Therapy for West Syndrome: A Finnish Perspective

West syndrome, a severe form of epilepsy characterized by spasms, is a challenging condition to treat. This study, conducted in Finland, explores the efficacy and tolerability of adrenocorticotropic hormone (ACTH) therapy in managing West syndrome. The researchers reviewed Finnish studies on ACTH therapy, comparing its effectiveness to vigabatrin (VGB), another anti-epileptic medication. The study found that ACTH therapy, when administered at doses of 3-6 IU/kg/day, effectively controlled spasms in a significant proportion of patients, with minimal side effects. The study also found that some patients who did not respond to VGB as a first-line treatment showed improvement with ACTH. The authors highlight the importance of individualized therapy based on the etiology and response of each patient. This research provides valuable insights into the use of ACTH in managing West syndrome.

ACTH Therapy: A Promising Option for West Syndrome

This research suggests that ACTH therapy can be an effective treatment for West syndrome, particularly in patients who do not respond well to other anti-epileptic medications. However, it's important to note that the study was conducted on a specific population in Finland, and further research is needed to confirm these findings in other populations.

Navigating the Complexities of Epilepsy Management

West syndrome, like a desert mirage, can appear elusive and challenging to manage. This research emphasizes the importance of a multi-faceted approach to epilepsy management, including considering various treatment options and tailoring therapy to individual patient needs.

Dr.Camel's Conclusion

West syndrome is a formidable foe, but this research offers a beacon of hope in the form of ACTH therapy. As we delve deeper into the complexities of epilepsy, we can discover even more effective strategies for managing this challenging condition and improving the lives of those affected.
Date :
  1. Date Completed 2002-02-20
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

11701269

DOI: Digital Object Identifier

10.1016/s0387-7604(01)00306-0

Related Literature

SNS
PICO Info
in preparation
Languages

English

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