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Vigabatrin for tuberous sclerosis complex.

Author: BombardieriR, CuratoloP, VerdecchiaM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article reviews the clinical and basic science investigations regarding the safety and efficacy of vigabatrin in the treatment of infantile spasms.
Paper Details　
Original Abstract of the Article :
Vigabatrin (VGB) was found to be an effective anti-epileptic drug to reduce infantile spasms in about 50% of patients and it has been found most effective in infantile spasms due to tuberous sclerosis (TSC) in which up to 95% of infants had complete cessation of their spasms. VGB was synthesized to ...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1016/s0387-7604(01)00290-x

データ提供：米国国立医学図書館（NLM）

Vigabatrin for Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is a rare genetic disorder that can lead to a range of health challenges, including seizures. This study explores the use of vigabatrin (VGB), an anti-epileptic drug, in the treatment of infantile spasms associated with TSC. The study provides valuable insights into the effectiveness of VGB in treating infantile spasms in patients with TSC.

Vigabatrin - A Promising Treatment for Infantile Spasms in TSC

The study found that VGB was effective in reducing infantile spasms in infants with TSC. VGB's effectiveness suggests that epileptogenesis in TSC may be related to an impairment of GABAergic transmission. The findings provide promising evidence for the use of VGB in treating infantile spasms in patients with TSC.

A Valuable Tool for Managing Infantile Spasms

VGB has shown to be a valuable tool for managing infantile spasms in TSC. The study highlights the importance of early intervention and the potential of this drug to improve outcomes for infants with TSC.

Dr. Camel's Conclusion

This study underscores the importance of finding effective treatments for rare diseases like TSC. VGB offers a potential solution for managing infantile spasms in patients with TSC, offering hope for improved outcomes for infants and their families. It's like finding a rare and precious oasis in the vast and often unforgiving desert of medical challenges.

Date :
  1. Date Completed 2002-02-20
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

11701271

DOI: Digital Object Identifier

10.1016/s0387-7604(01)00290-x

Related Literature

Article Analysis
・Side Effects of vigabatrin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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