Therapeutic drug monitoring of HIV protease inhibitors using high-performance liquid chromatography with ultraviolet or photodiode array detection.

Author: Autret-LecaE, BastidesF, BesnierJ M, GaudetM L, Le GuellecC, LeibenguthP, MacéM, PaintaudG

Paper Details 
Original Abstract of the Article :
Published data suggest that therapeutic drug monitoring of human immunodeficiency virus protease inhibitors would improve the management of antiretroviral therapy. The authors have developed a high-pressure liquid chromatographic assay allowing simultaneous determination of six protease inhibitors (...See full text at original site
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引用元:
https://doi.org/10.1097/00007691-200112000-00015

データ提供:米国国立医学図書館(NLM)

Therapeutic Drug Monitoring of HIV Protease Inhibitors: A Beacon in the Desert of HIV Treatment

The field of [HIV treatment] is a vast desert, where the [complexities] of [viral suppression] and [drug interactions] can be overwhelming. This study, a beacon in the [desert of HIV management], explores the importance of [therapeutic drug monitoring] for [HIV protease inhibitors]. The authors, like skilled desert navigators, develop a [high-pressure liquid chromatographic assay] for the [simultaneous determination] of [six protease inhibitors], providing a valuable tool for [optimizing treatment strategies] and [monitoring patient outcomes].

Navigating the Desert of HIV Treatment: The Importance of Therapeutic Drug Monitoring

This study underscores the [importance] of [therapeutic drug monitoring] for [HIV protease inhibitors], demonstrating the potential of [drug monitoring] to [improve the management] of [antiretroviral therapy]. The authors' findings highlight the [critical need] to ensure that [patients] receive the [appropriate dosage] of [medication], maximizing [viral suppression] and [minimizing side effects].

Guiding Patients Through the Desert of HIV Management: A Personalized Approach to Treatment

This research emphasizes the [importance] of a [personalized approach] to [HIV treatment], recognizing that [patients] may respond differently to [medications]. By [monitoring drug levels] and [adjusting treatment strategies] accordingly, healthcare professionals can help [patients] navigate the [challenges] of [HIV management] and achieve [optimal health outcomes]. This study is a reminder that [close monitoring] and [individualized care] are essential for [effectively treating] this [complex disease].

Dr.Camel's Conclusion

This research journey through the [desert of HIV treatment] highlights the [critical role] of [therapeutic drug monitoring] in [optimizing patient outcomes]. The authors' work underscores the importance of [individualized care] and [close monitoring] in [managing this complex disease]. By [embracing] the [power of drug monitoring], we can [improve the effectiveness] of [HIV treatment], offering [hope] and [improved quality of life] for those living with this [disease].

Date :
  1. Date Completed 2002-03-07
  2. Date Revised 2019-09-06
Further Info :

Pubmed ID

11802104

DOI: Digital Object Identifier

10.1097/00007691-200112000-00015

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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