Paper Details
- Home
- Paper Details
Comparison of long lasting therapeutic effects between succimer and penicillamine on hepatolenticular degeneration.
Author: LiFei, RenMing-Shan, WuJun-Xia, XueBen-Chun, YangRen-Min, ZhangZhi
Original Abstract of the Article :
AIM:To compare the long-term effect of succimer (Suc) with that of penicillamine (Pen) in treating hepatolenticular degeneration (HLD).METHODS:One hundred and twenty patients with HLD were divided into 2 groups. Group A (n =60) received Suc 750mg,po.bid.Group B (n =60) received Pen 250mg, po. qid. T...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3748/wjg.v4.i6.530
データ提供:米国国立医学図書館(NLM)
Succimer vs. Penicillamine: A Showdown in the Desert of Hepatolenticular Degeneration
Hepatolenticular degeneration, also known as Wilson's disease, is a rare genetic disorder that disrupts the body's ability to process copper. This study compares the long-term efficacy and safety of two medications, succimer (Suc) and penicillamine (Pen), in treating this complex condition. Like two rival explorers vying for dominance in a vast desert, researchers meticulously analyzed the clinical outcomes of these medications, seeking the most effective route to combat Wilson's disease.
Succimer Emerges Victorious: A Triumph in the Desert
The study found that succimer was significantly more effective than penicillamine in treating hepatolenticular degeneration. Succimer achieved higher rates of overall effectiveness and also demonstrated a favorable safety profile with fewer side effects. Succimer also proved beneficial for patients who had previously failed to respond to penicillamine treatment. Think of succimer as a resourceful explorer who navigates the challenges of Wilson's disease with greater success, while penicillamine struggles to overcome the harsh terrain.
Succimer: A Promising Weapon in the Arsenal Against Wilson's Disease
This study provides compelling evidence that succimer is a more effective and safer treatment option for hepatolenticular degeneration than penicillamine. The findings suggest that succimer should be considered the first-line therapy for long-term maintenance treatment of this condition. However, it is important to note that this study was conducted in a specific patient population, and further research is needed to confirm these findings in other groups.
Dr. Camel's Conclusion
This study is like a pivotal battle in the desert of Wilson's disease research. Succimer emerges as a formidable warrior, demonstrating superior efficacy and safety compared to penicillamine. While further research is needed to solidify its position as the gold standard treatment, this study offers a promising path towards effective and safe management of this complex condition.
Date :
- Date Completed n.d.
- Date Revised 2019-11-20
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.