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Effects of rivastigmine on cognitive function in dementia with lewy bodies: a randomised placebo-controlled international study using the cognitive drug research computerised assessment system.
Author: AnandR, Cicin-SainA, Del SerT, EmreM, FerraraR, McKeithI G, SpanoP F, SpiegelR, WesnesK A
Original Abstract of the Article :
This study was designed to assess the effects of rivastigmine (Exelon) on the cognitive functioning of patients suffering from dementia with Lewy bodies. This was a prospective, multi-centre, randomised, double-blind, placebo-controlled exploratory study conducted at sites in the UK, Spain and Italy...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000048651
データ提供:米国国立医学図書館(NLM)
Rivastigmine: A Potential Oasis for Cognitive Function in Dementia with Lewy Bodies
Dementia with Lewy bodies (DLB) is a neurodegenerative disorder that can significantly impact cognitive function. This research investigates the effects of rivastigmine, a cholinesterase inhibitor, on cognitive function in patients with DLB.
The researchers conducted a randomized, double-blind, placebo-controlled study. Their findings indicate that rivastigmine treatment resulted in significant improvements in cognitive function compared to placebo, particularly in areas such as [attention], [working memory], and [episodic secondary memory]. These improvements were observed on the [Cognitive Drug Research (CDR) computerized assessment system].
Hope on the Horizon for DLB Treatment
This study offers hope for patients with DLB, suggesting that rivastigmine can help to improve cognitive function and potentially slow the progression of the disease. However, it is important to note that the effects of rivastigmine were not long-lasting, and further research is needed to explore the long-term efficacy of this treatment.
A Collaborative Approach to Managing DLB
Managing DLB requires a multidisciplinary approach, involving healthcare professionals, family members, and caregivers. Open communication and support are essential for helping individuals with DLB maintain their quality of life.
Dr.Camel's Conclusion
This research is like a cool spring in the hot desert of DLB. While it doesn't offer a cure, it provides hope for improving cognitive function and potentially slowing the progression of this debilitating disease. It underscores the importance of ongoing research and development of new treatments for DLB.
Date :
- Date Completed 2002-05-09
- Date Revised 2017-11-01
Further Info :
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