Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial.

Author: AltenR, BrandtJ, BraunJ, GolderW, Gromnica-IhleE, KellnerH, KrauseA, ListingJ, SchneiderM, SieperJ, SörensenH, ThrieneW, ZeidlerH, ZinkA

Paper Details 
Original Abstract of the Article :
UNLABELLED: BACKGROUND Treatment options for patients with ankylosing spondylitis are few. We aimed to assess the effectiveness of infliximab, an antibody to tumour necrosis factor (TNF)-alpha, in treatment of such patients. METHODS: In this 12-week placebo-controlled multicentre study, we randomly...See full text at original site
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引用元:
https://doi.org/10.1016/s0140-6736(02)08215-6

データ提供:米国国立医学図書館(NLM)

Infliximab: A Potential Oasis in the Desert of Ankylosing Spondylitis

The desert of [ankylosing spondylitis] can be a difficult and painful landscape to navigate. This study, like a caravan of researchers venturing into the unknown, examines the efficacy of [infliximab], an antibody to [tumor necrosis factor (TNF)-alpha], in treating [active ankylosing spondylitis]. The researchers sought to find a new path to relief for those suffering from this inflammatory disease.

A Beacon of Hope in the Desert: Infliximab Shows Promise

The study's findings, like a shimmering oasis in the desert, demonstrate that [infliximab] was significantly more effective than placebo in reducing disease activity, improving function, and enhancing quality of life in patients with [active ankylosing spondylitis]. However, it's crucial to acknowledge the potential side effects, which, like shifting desert sands, can change the landscape of treatment.

A Path to Relief: Navigating the Desert of Ankylosing Spondylitis

The study's findings offer a glimpse of hope for those struggling with [ankylosing spondylitis]. [Infliximab] could provide a new path to relief, lessening pain and improving overall well-being. However, like any journey through the desert, it's important to be aware of the potential risks and to consult with healthcare professionals to make informed decisions about treatment options.

Dr.Camel's Conclusion

The desert of [ankylosing spondylitis] is a difficult place to traverse. This study, like a well-stocked camel caravan, brings hope for those facing this challenge. [Infliximab] appears to be a promising treatment option, offering a potential oasis of relief for those seeking a path to improved health and quality of life. However, as with any journey, it's crucial to be aware of the potential hazards and to proceed with caution and expert guidance.

Date :
  1. Date Completed 2002-04-25
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

11955536

DOI: Digital Object Identifier

10.1016/s0140-6736(02)08215-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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