[Methemoglobinemia induced by repeated abuse of lidocaine viscous gel].

Author: BorelM, GoulleJ, LacroixC, PeureuxM

Paper Details 
Original Abstract of the Article :
Lidocaine use may lead to methemoglobinemia. Lidocaine is clinically widely used as an anaesthesic drug, however its toxic effect is rare. We report a high methemoglobinemia level of 31.1% following repeated Xylocaine gel oral applications. New metabolic pathways of lidocaine have been reported lead...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/11974447

データ提供:米国国立医学図書館(NLM)

Methemoglobinemia: A Rare but Potentially Serious Side Effect of Lidocaine

The field of methemoglobinemia research explores the rare but potentially serious condition where the oxygen-carrying capacity of red blood cells is reduced. This case report examines a high methemoglobinemia level in a patient following repeated abuse of lidocaine viscous gel. The authors investigate the potential mechanisms underlying lidocaine-induced methemoglobinemia and highlight the importance of recognizing this potential side effect.

Lidocaine: Unexpected Effects in the Desert of Medication Use

The study found that repeated oral applications of lidocaine viscous gel led to a high methemoglobinemia level, highlighting the potential for lidocaine, a commonly used anesthetic drug, to induce this condition. The authors proposed a potential mechanism involving the formation of dimethylphenylhydroxylamine, a metabolite of lidocaine that may have similar effects to aniline derivatives known to induce methemoglobinemia.

Health Implications

This case report underscores the importance of being aware of the potential for lidocaine to induce methemoglobinemia, particularly in cases of repeated or prolonged use. Healthcare professionals should be vigilant in monitoring patients for signs and symptoms of methemoglobinemia, ensuring prompt diagnosis and treatment if necessary.

Dr.Camel's Conclusion

This case report serves as a reminder that even seemingly safe medications can have unexpected side effects. It highlights the importance of careful monitoring for potential adverse reactions, particularly in cases of prolonged or repeated use of medications. Healthcare professionals must be aware of the potential for methemoglobinemia with lidocaine use and take appropriate steps to ensure patient safety.

Date :
  1. Date Completed 2002-06-19
  2. Date Revised 2016-03-14
Further Info :

Pubmed ID

11974447

DOI: Digital Object Identifier

11974447

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SNS
PICO Info
in preparation
Languages

French

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