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Long-term protection in at-risk hypertensive patients--a role for nifedipine GITS?

Author: RuilopeLuis M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The INSIGHT study compared the effectiveness of nifedipine GITS (a long-acting formulation) and co-amilozide (a diuretic) in preventing cardiovascular events in high-risk hypertensive patients. Both treatments were equally effective in preventing overall cardiovascular or cerebrovascular complications, including in patients with diabetes. Nifedipine GITS was more effective at preventing carotid artery thickening and slowing coronary calcification progression.
Paper Details　
Original Abstract of the Article :
Hypertensive patients who are at high risk of developing cardiovascular (CV) complications have become the focus of modern treatment guidelines. The choice of antihypertensive therapies in these patients should be evidence-based: in particular, there should be evidence of a beneficial impact on CV e...See full text at original site
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引用元：
https://doi.org/10.1080/08037050211264

データ提供：米国国立医学図書館（NLM）

Nifedipine GITS: A Potential Solution for High-Risk Hypertension

High-risk hypertension, a significant public health concern, requires effective treatment to prevent cardiovascular complications. This study investigates the use of nifedipine GITS, a long-acting formulation of nifedipine, for managing high-risk hypertension. Researchers conducted a large, randomized, double-blind study comparing nifedipine GITS to a diuretic (co-amilozide) in patients with high-risk hypertension.

Nifedipine GITS: A Promising Treatment for High-Risk Hypertension

The study found that nifedipine GITS and co-amilozide were equally effective in preventing cardiovascular and cerebrovascular complications in patients with high-risk hypertension. The study also showed that nifedipine GITS was more effective in preventing the progression of atherosclerosis, a key factor contributing to cardiovascular disease.

Navigating the Desert of Hypertension: Finding the Right Treatment

This research provides valuable insights into the management of high-risk hypertension. Nifedipine GITS appears to be a promising treatment option, offering effective blood pressure control and potential benefits in preventing cardiovascular disease. It's important to consult with healthcare professionals to determine the best treatment strategy for individual needs.

Dr.Camel's Conclusion

High-risk hypertension can be a challenging condition, but this study offers a glimmer of hope. Nifedipine GITS appears to be a viable treatment option for patients with high-risk hypertension. It's a reminder that the desert of cardiovascular health can be navigated with the right tools and expert guidance.

Date :
  1. Date Completed 2002-12-19
  2. Date Revised 2019-11-06
Further Info :

Pubmed ID

12035870

DOI: Digital Object Identifier

10.1080/08037050211264

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