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[Clinical studies using the combination atovaquone-proguanil as malaria prophylaxis in non-immune adult and child travelers].

Author: CamusD, DelhaesL, DutoitE, InglebertP, MassonV

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Malarone (atovaquone/proguanil) is a promising antimalarial drug for short-term travel to malaria-endemic areas. It is effective against multidrug-resistant strains of Plasmodium falciparum and has a convenient single-dose administration, leading to good compliance. Malarone is well tolerated by adults and children.
Paper Details　
Original Abstract of the Article :
Prophylaxis for short-term travel in malaria-endemic areas can be difficult for two reasons. The first is that currently available antimalarial drugs are becoming less effective because of the ability of the parasite to adapt to drug pressure. The second involves poor compliance with chemoprophylact...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12244915

データ提供：米国国立医学図書館（NLM）

Combating Malaria: A Journey Through Resistance and Prevention

Malaria, a deadly disease spread by mosquitoes, poses a significant threat to travelers visiting endemic regions. Finding effective and well-tolerated treatments for this parasitic infection is a constant challenge, particularly with the emergence of drug-resistant strains.

This research explores the potential of the drug combination atovaquone/proguanil (Malarone) as a prophylactic treatment for malaria. The study highlights the drug's effectiveness against multiresistant strains of Plasmodium falciparum, the most dangerous type of malaria parasite.

A Promising Solution for Malaria Prevention

This research offers a potential solution to the growing challenge of drug resistance in malaria. The study suggests that atovaquone/proguanil could be a valuable tool for preventing malaria in travelers.

Protecting Yourself from Malaria: Travel Wisely

This research emphasizes the importance of taking appropriate precautions when traveling to malaria-endemic areas. It's crucial to consult with a healthcare professional to receive the proper guidance and medication for malaria prevention.

Dr. Camel's Conclusion

Navigating the desert of malaria prevention can be challenging, but this research offers a promising oasis – atovaquone/proguanil. By staying informed about the latest treatment options and taking necessary precautions, we can minimize the risks associated with this potentially life-threatening disease.
Date :
  1. Date Completed 2002-10-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12244915

DOI: Digital Object Identifier

12244915

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PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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