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Synthesis of targeted drug delivery system for fluorouracil using sulfadiazine as the carrier.

Author: CaoMan-Ming, HuXi-Gang, LuYang, WangSen-Ming, ZhangQi-Xing

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A targeted drug delivery system for 5-fluorouracil using sulfadiazine as a carrier has been successfully synthesized.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To synthesize a targeted drug delivery system for 5-fluorouracil (5Fu) using sulfadiazine (SF) as a carrier with reduced side-effects and strong antitumor activity. METHODS: SF-poly (ethylene glycol) (PEG) conjugate was initially synthesized. 5Fu was subjected to reaction with trichlorom...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12433646

データ提供：米国国立医学図書館（NLM）

Targeted Drug Delivery for Fluorouracil: A New Approach

This research explores the development of a targeted drug delivery system for fluorouracil (5Fu), a chemotherapy drug used to treat various cancers. The authors aimed to improve the effectiveness and reduce the side effects of 5Fu by creating a delivery system that specifically targets cancer cells. They synthesized a conjugate using sulfadiazine (SF) as a carrier, linking it to 5Fu via polyethylene glycol (PEG). This system was designed to deliver 5Fu directly to cancer cells, minimizing exposure to healthy tissues.

Targeted Drug Delivery: Precision in the Desert of Cancer Treatment

The research highlights the potential of targeted drug delivery systems in improving cancer treatment. By delivering the chemotherapy drug directly to cancer cells, this system could potentially minimize side effects and enhance the effectiveness of treatment. It's like using a precise GPS system to navigate the desert, ensuring that resources are delivered to the intended destination.

Innovation in Cancer Treatment: A Journey Towards Better Outcomes

This research demonstrates the ongoing innovation in the field of cancer treatment, exploring new ways to deliver medications and improve patient outcomes. The authors' findings suggest that targeted drug delivery systems could play a significant role in the future of cancer care.

Dr.Camel's Conclusion

This research explores the potential of a targeted drug delivery system for fluorouracil (5Fu), using sulfadiazine as a carrier. The findings suggest that this system could potentially improve the effectiveness of 5Fu while minimizing side effects, highlighting the importance of ongoing innovation in the field of cancer treatment.

Date :
  1. Date Completed 2003-01-27
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

12433646

DOI: Digital Object Identifier

12433646

Related Literature

Article Analysis
・Side Effects of sulfadiazine
SNS
PICO Info
in preparation
Languages

English

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