Clinical lipoatrophy in HIV-1 patients on HAART is not associated with increased abdominal girth, hyperlipidaemia or glucose intolerance.

Author: AndersenO, GerstoftJ, KatzensteinT L, KirkO, NielsenH, PedersenC, VintenJ, WormD

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare information on body fat changes from questionnaire and clinical examination and to study lipoatrophy in HIV-1 patients on highly active antiretroviral therapy (HAART). METHODS: The study was cross-sectional within a randomized trial. One hundred and sixty-eight male HIV-1 pati...See full text at original site
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引用元:
https://doi.org/10.1046/j.1468-1293.2002.00125.x

データ提供:米国国立医学図書館(NLM)

Lipoatrophy in HIV-1 Patients: A Complex Side Effect

Highly active antiretroviral therapy (HAART) has revolutionized the treatment of HIV-1 infection, dramatically improving the lives of patients. However, HAART can come with side effects, including lipoatrophy, a condition characterized by fat loss in specific areas of the body. This study, conducted in the field of infectious diseases, investigated the prevalence of lipoatrophy in HIV-1 patients on HAART and its association with metabolic parameters. The study found that 14% of patients on HAART experienced lipoatrophy, which was associated with lower weight, lower circumferences, and lower levels of triglycerides and LDL cholesterol. Interestingly, the study found no association between lipoatrophy and increased abdominal girth, hyperlipidemia, or glucose intolerance.

Lipoatrophy: A Complex Side Effect of HAART

The study's findings highlight the complex nature of lipoatrophy in HIV-1 patients on HAART. While lipoatrophy was associated with certain metabolic parameters, it was not linked to other expected complications like abdominal obesity or metabolic syndrome. This research underscores the need for a nuanced understanding of the potential side effects of HAART and individualized care plans to address these concerns. It's like navigating a desert oasis, where the benefits are significant, but the landscape is dotted with unforeseen hazards.

Managing Lipoatrophy: A Collaborative Approach

For individuals with HIV-1 on HAART, it's crucial to stay in close communication with your healthcare provider to monitor for lipoatrophy and to discuss strategies for managing potential side effects. The study's findings highlight the importance of a collaborative approach to HIV-1 care, ensuring that patients are informed about potential side effects and receive personalized care to manage them effectively. It's a reminder that the journey through the desert of HIV-1 treatment requires vigilance and personalized care to address the unique challenges faced by each individual.

Dr.Camel's Conclusion

This study underscores the importance of understanding the potential side effects of HAART and developing strategies for managing lipoatrophy in HIV-1 patients. The findings highlight the need for a nuanced understanding of lipoatrophy and individualized care plans to address this complex side effect. It's a reminder that the journey through the desert of HIV-1 treatment requires ongoing vigilance and careful attention to potential challenges along the way.

Date :
  1. Date Completed 2003-01-22
  2. Date Revised 2019-11-06
Further Info :

Pubmed ID

12444941

DOI: Digital Object Identifier

10.1046/j.1468-1293.2002.00125.x

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SNS
PICO Info
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Languages

English

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