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Initial treatment dose of L-thyroxine in congenital hypothyroidism.

Author: LafranchiStephen H, MandelScott H, MiyahiraRichard, NelsonJerald C, RienLeanne, SelvaKarin A, SesserDavid, SkeelsMichael

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study aims to determine the optimal initial treatment dose of L-thyroxine in congenital hypothyroidism (CH) and to re-evaluate the target range for thyroxine (T(4)) and free T(4) concentrations.
Paper Details　
Original Abstract of the Article :
To determine the optimal initial treatment dose of L-thyroxine in congenital hypothyroidism (CH) by evaluating the time course of rise of thyroxine (T(4)) and free T(4) concentrations into an established "target range" and normalization of thyroid-stimulating hormone (TSH) and to reevaluate the "tar...See full text at original site
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引用元：
https://doi.org/10.1067/mpd.2002.128887

データ提供：米国国立医学図書館（NLM）

Congenital Hypothyroidism: Navigating the Desert of Hormone Treatment

Congenital hypothyroidism (CH) is a condition that affects thyroid hormone production in newborns, potentially leading to developmental delays. This study explores the optimal initial treatment dose of L-thyroxine, a synthetic thyroid hormone, in newborns with CH. Imagine researchers as explorers, navigating the vast desert of hormone treatment, seeking the right dose to ensure optimal development for infants with CH.

Finding the Right Dose: A Crucial Oasis in the Desert

The researchers studied the time course of thyroid hormone levels in infants with CH after receiving different initial doses of L-thyroxine. The study aimed to identify the optimal dose that quickly achieves and maintains normal thyroid hormone levels. Finding the right dose is like finding a crucial oasis in the desert, ensuring the infant's journey to healthy development.

Early Intervention: A Key to Success in the Desert

This research underscores the importance of early intervention and accurate dosing in treating CH. Finding the optimal initial dose of L-thyroxine can significantly improve the outcomes for infants with CH, ensuring their healthy development. It's like providing a timely and accurate guide to help these infants navigate the desert of development successfully.

Dr.Camel's Conclusion

The desert of CH treatment is a delicate landscape, and finding the right dose of L-thyroxine is a crucial step in ensuring optimal development for infants with this condition. This research provides valuable insights for healthcare providers, offering a roadmap to successful treatment and a better future for infants with CH.

Date :
  1. Date Completed 2003-01-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12461494

DOI: Digital Object Identifier

10.1067/mpd.2002.128887

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・Effective treatment of hypothyroidism
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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