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St John's wort: a systematic review of adverse effects and drug interactions for the consultation psychiatrist.

Author: , BarretteE-P, BaschEthan, BaschSamuel, BentSteve, BoonHeather, ErnstEdzard, FoppaIvo, HammernessPaul, UlbrichtCatherine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

St. John's wort, a herb used for depression, has shown to be more effective than placebo and as effective as tricyclic antidepressants for short-term treatment of mild to moderate depression. While it is generally well-tolerated, it has significant interactions with other medications. This review summarizes the information on its mechanisms, clinical uses, and potential side effects, toxicity, and drug interactions.
Paper Details　
Original Abstract of the Article :
St. John's wort is an herb commonly used in Europe for decades and more recently the topic of scientific investigation in this country. St. John's wort has been found more effective than placebo and equally as effective as tricyclic antidepressants in the short-term management of mild-to-moderate de...See full text at original site
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引用元：
https://doi.org/10.1176/appi.psy.44.4.271

データ提供：米国国立医学図書館（NLM）

St. John's Wort: A Natural Remedy for Depression

St. John's wort, a plant with vibrant yellow flowers, has been used for centuries as a natural remedy. In recent years, it has become a subject of scientific investigation, particularly for its potential to treat depression. This research, like a camel's journey across the desert, meticulously reviews the literature on St. John's wort's potential effects, from its effectiveness to its interactions with other medications.

St. John's Wort's Effectiveness and Interactions

The researchers found that St. John's wort shows promise as a treatment for mild-to-moderate depression, performing better than a placebo and on par with traditional tricyclic antidepressants. However, the research also highlights a critical point: St. John's wort can interact with other medications in surprising ways, much like how a camel might encounter an unexpected sandstorm. This interaction potential is a key consideration for anyone contemplating using St. John's wort.

Navigating the Desert of Depression

The study emphasizes the need for caution when considering natural remedies. While St. John's wort might offer a natural route to treating depression, it's crucial to consult a healthcare professional to assess potential interactions with other medications. A doctor can help navigate the desert of depression and find the right path to well-being, just as a skilled camel guide can lead you safely across the dunes.

Dr. Camel's Conclusion

St. John's wort is a promising natural remedy for depression, but it's essential to approach it with caution due to its potential interactions with other medications. Consulting a healthcare professional can help you weigh the benefits and risks of using St. John's wort, ensuring a safe and successful journey toward a healthier state of mind.

Date :
  1. Date Completed 2003-08-19
  2. Date Revised 2019-11-07
Further Info :

Pubmed ID

12832592

DOI: Digital Object Identifier

10.1176/appi.psy.44.4.271

SNS
PICO Info
in preparation
Languages

English

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