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Treatment of mycosis fungoides with oral bexarotene combined with PUVA.

Author: LebwohlMark, SternDana Kaslow

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Bexarotene is a retinoid drug used to treat cutaneous T-cell lymphoma (CTCL). This study describes a patient with mycosis fungoides who responded well to a combination of low-dose bexarotene and PUVA.
Paper Details　
Original Abstract of the Article :
Bexarotene has recently been approved in the United States and Europe as a single orally administered retinoid for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. We describe a 47-year old female with a 4-year history of mycosi...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12847736

データ提供：米国国立医学図書館（NLM）

Bexarotene and PUVA: A Novel Combination for Mycosis Fungoides Treatment

Mycosis fungoides, a type of cutaneous T-cell lymphoma, can be a challenging condition to treat. This study investigates the efficacy of a novel combination therapy involving bexarotene, a retinoid, and PUVA, a phototherapy treatment, in a patient with mycosis fungoides. The authors report a case study that demonstrates the potential of this combination for effectively managing the disease.

A Promising Approach for Mycosis Fungoides Treatment

The study highlights the effectiveness of the bexarotene-PUVA combination in a patient with mycosis fungoides who had previously experienced debilitating side effects from other treatments. The authors observed a significant improvement in the patient's condition, suggesting that this novel regimen could be a valuable option for treating patients with this challenging disease.

Navigating Treatment Options for Mycosis Fungoides

The case study underscores the importance of personalized treatment approaches for patients with mycosis fungoides. Just as a desert traveler adapts to the changing landscape, patients with this disease may need tailored therapies to find the most effective route to recovery. This research paves the way for further exploration of combination therapies like bexarotene-PUVA, offering hope to individuals seeking relief from this condition.

Dr.Camel's Conclusion

This study demonstrates the importance of innovation and flexibility in treating complex diseases. The combination of bexarotene and PUVA offers a new pathway for managing mycosis fungoides, providing hope for patients seeking effective and well-tolerated treatments. This research is a reminder that even in the vast desert of medical knowledge, new discoveries can emerge to provide life-changing solutions.
Date :
  1. Date Completed 2003-07-24
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

12847736

DOI: Digital Object Identifier

12847736

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Article Analysis
・Side Effects of bexarotene
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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