Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis: an open, observational, extension study of a three-month, randomized, placebo-controlled trial.

Author: AltenR, BrandtJ, BraunJ, BurmesterG, GolderW, Gromnica-IhleE, KellnerH, ListingJ, ReddigJ, SchneiderM, SieperJ, SörensenH, ZeidlerH, ZinkA

Paper Details 
Original Abstract of the Article :
Treatment of ankylosing spondylitis (AS) with infliximab, an anti-tumor necrosis factor alpha monoclonal antibody, was shown to be efficacious in patients with active disease during a 3-month treatment period. The purpose of this study was to evaluate the efficacy and safety of infliximab treatment ...See full text at original site
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引用元:
https://doi.org/10.1002/art.11104

データ提供:米国国立医学図書館(NLM)

Long-Term Efficacy and Safety of Infliximab in Ankylosing Spondylitis

The realm of rheumatology is constantly evolving, with researchers diligently seeking effective treatments for inflammatory conditions like ankylosing spondylitis (AS). This particular study delves into the long-term efficacy and safety of infliximab, an anti-tumor necrosis factor alpha monoclonal antibody, for treating AS. The researchers employed a rigorous, open observational extension study design, building upon a previous three-month randomized placebo-controlled trial. Their primary goal was to assess the long-term impact of infliximab on AS patients over a one-year period.

Infliximab Shows Promise in Managing Ankylosing Spondylitis

The study revealed that infliximab continued to demonstrate efficacy in managing AS symptoms over a year, providing hope for patients seeking long-term relief. This positive outcome underscores the potential of this medication as a valuable tool for managing chronic inflammatory conditions.

Living Well with Ankylosing Spondylitis

While infliximab offers promise for managing AS, it is important to remember that it's not a cure-all. It's crucial to consult with a healthcare professional to determine if infliximab is the right treatment for you. Moreover, lifestyle modifications, including regular exercise and a healthy diet, can play a vital role in managing AS and promoting overall well-being.

Dr. Camel's Conclusion

This research, like a desert oasis providing much-needed hydration, offers hope for patients with AS. Infliximab's long-term efficacy, while not a cure, is a significant step forward in managing this debilitating condition. It's like finding a rare desert flower amidst the harsh landscape - a sign of resilience and potential.

Date :
  1. Date Completed 2003-08-29
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

12905476

DOI: Digital Object Identifier

10.1002/art.11104

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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