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Comparative clinical profiles of triazolam versus other shorter-acting hypnotics.
Author: ColemanB S, JonasJ M, KalinskeR W, SheridanA Q
Original Abstract of the Article :
The efficacy, safety, and performance of triazolam was compared with those of other shorter-acting hypnotics acting on the gamma-aminobutyric acid (GABA) receptor--zopiclone, zolpidem, midazolam, brotizolam, temazepam, lormetazepam, and loprazolam. In all, 5506 patients participated in 38 clinical a...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1336776
データ提供:米国国立医学図書館(NLM)
Triazolam and Other Hypnotics: Comparing Efficacy and Safety
In the field of sleep medicine, the search for effective and safe hypnotics is an ongoing journey. This study compared the efficacy, safety, and performance of triazolam to other short-acting hypnotics, including zopiclone, zolpidem, midazolam, brotizolam, temazepam, lormetazepam, and loprazolam. The researchers analyzed data from 38 clinical and epidemiological studies involving 5506 patients, with 2462 receiving triazolam. The study found no evidence of 'serious' central nervous system side effects, such as excitement or violence, with any of the hypnotic agents, including triazolam. Additionally, the study found remarkable similarities in terms of efficacy, side effects, and performance-related effects across all the shorter-acting agents, with zopiclone and zolpidem showing particular resemblance to triazolam.Unveiling the Similarities in Hypnotic Medications
The study's findings highlight the similarities in the clinical and pharmacological profiles of various short-acting hypnotics, regardless of their chemical structure. These findings challenge previous assumptions about distinct effects associated with different drug classes and emphasize the importance of considering individual patient factors when selecting a suitable hypnotic medication.Navigating the World of Sleep Aids: A Practical Approach
This study provides valuable information for patients and healthcare professionals seeking effective and safe sleep medications. It suggests that while individual preferences and sensitivities may vary, there is a remarkable consistency in the overall effects of short-acting hypnotics. It's essential to consult with a healthcare professional to determine the most appropriate sleep aid for individual needs and to discuss potential risks and benefits.Dr. Camel's Conclusion
My dear friends, navigating the world of sleep aids can feel like traversing a vast desert with many paths. This study helps us understand that while the paths may seem different, they often lead to similar destinations. Remember to consult your doctor before embarking on any sleep-related journey, and choose the path that best suits your needs. Rest assured, there is a place for everyone to find restful slumber in the desert of sleep.Date :
- Date Completed 1993-02-23
- Date Revised 2018-11-30
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