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One-minute dithranol therapy in psoriasis: a placebo-controlled paired comparative study.

Author: JeklerJ, SwanbeckG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Dithranol 2% ointment was more effective than placebo in clearing or improving psoriasis plaques in 27 patients with chronic plaque psoriasis vulgaris. Dithranol significantly reduced erythema, infiltration, scaling, and pruritus, with minimal side effects.
Paper Details　
Original Abstract of the Article :
In a double-blind left-right randomised comparison, 27 patients suffering from chronic plaque-type psoriasis vulgaris were treated for one minute with dithranol 2% ointment, Psoralon (Psoralon MT), on a selected psoriasis plaque on one half of the body and with a placebo ointment on a corresponding ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1362841

データ提供：米国国立医学図書館（NLM）

One-Minute Dithranol Therapy for Psoriasis: A Promising Treatment

Psoriasis, a chronic inflammatory skin condition, can be a real desert of discomfort for those who suffer from it. This research is a beacon of hope in this arid landscape, investigating the effectiveness of a short-term dithranol therapy for psoriasis. The study, a double-blind trial, involved 27 participants who were randomly assigned to receive either a one-minute application of dithranol ointment or a placebo on their psoriasis plaques. After eight weeks, the results were quite striking: a significant percentage of patients in the dithranol group experienced clearing or considerable improvement compared to the placebo group. This suggests that even a brief, one-minute application of dithranol can have a significant impact on psoriasis.

A Short-Term Therapy with Significant Results

The study revealed that dithranol therapy led to statistically significant improvements in all aspects of psoriasis assessed, including redness, infiltration, scaling, and itching. The average score for these factors also showed a marked improvement in the dithranol group. This means that even a short-term dithranol therapy can offer relief and improvement in various symptoms associated with psoriasis.

Exploring the Oasis of Relief

The study highlights a potential oasis of relief for psoriasis patients. While dithranol therapy was effective, it's important to note that some patients did experience mild side effects, such as staining of clothes and bathrooms. However, no serious medical side effects were observed. This study suggests that one-minute dithranol therapy could be a valuable addition to the existing treatment options for psoriasis, offering a potential oasis of relief for those struggling with this condition.

Dr. Camel's Conclusion

This study sheds light on the potential of short-term dithranol therapy for psoriasis. While further research is needed to explore the long-term effects and optimize treatment protocols, these findings offer a promising avenue for those seeking relief from this chronic condition. It’s like finding a refreshing spring in the middle of a vast desert. Remember, the journey through the desert of psoriasis is often long and arduous, but with persistence and innovative treatments, a brighter, healthier horizon is always within reach!
Date :
  1. Date Completed 1993-03-04
  2. Date Revised 2021-01-13
Further Info :

Pubmed ID

1362841

DOI: Digital Object Identifier

102340/0001555572449450

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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