The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infections.

Author: BenslerJ Michael, BruceMichael G, BrudenDana L, ButlerJay C, HennessyThomas W, HurlburtDebby A, McMahonBrian J, MorrisJulie M, ParkinsonAlan J, ReasonoverAlisa L, SaccoFrank

Paper Details 
Original Abstract of the Article :
BACKGROUND: The relationship between previous antimicrobial treatments and infection with drug-resistant Helicobacter pylori is unknown. OBJECTIVES: To determine whether previous use of antimicrobial agents predicts subsequent antibiotic resistance of H. pylori and whether resistance affects treatm...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-139-6-200309160-00008

データ提供:米国国立医学図書館(NLM)

Helicobacter pylori: A Persistent and Elusive Foe

Helicobacter pylori, a bacterium that infects the stomach, is a major cause of gastritis and ulcers. This study investigates the relationship between previous antimicrobial use and the development of antimicrobial resistance in H. pylori infections. The researchers found that prior use of macrolides and metronidazole, common antibiotics for treating H. pylori infections, significantly increased the risk of resistance to these drugs, highlighting the challenges in managing this infection.

The Cycle of Resistance

The study's findings, like a desert cycle of drought and rain, demonstrate the complex interplay between antibiotic use and resistance. The overuse and misuse of antibiotics can lead to the emergence of resistant strains, posing a significant challenge to effective treatment.

The Importance of Prudent Antibiotic Use

This research underscores the critical importance of responsible antibiotic use. It highlights the need for healthcare providers to prescribe antibiotics only when necessary and to avoid unnecessary overuse. This approach can help prevent the emergence of resistant strains and ensure the effectiveness of antibiotics in treating bacterial infections.

Dr. Camel's Conclusion

This research, like a compass guiding us through the vast desert of antimicrobial resistance, highlights the crucial role of prudent antibiotic use in managing H. pylori infections. By understanding the complex interplay between antibiotic use and resistance, healthcare providers can develop more effective strategies for controlling this persistent and elusive foe.

Date :
  1. Date Completed 2003-09-29
  2. Date Revised 2019-06-19
Further Info :

Pubmed ID

13679322

DOI: Digital Object Identifier

10.7326/0003-4819-139-6-200309160-00008

SNS
PICO Info
in preparation
Languages

English

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