[Effect of indirect endolymphatic antibiotic therapy on clinical and immunological indicators in patients with erysipelas of the lower extremities].

Author: AmbalovIu M, AĭtkuluevN S, KovalenkoA P, LevinaL D, PoliakA I, UsatkinA V

Paper Details 
Original Abstract of the Article :
Two groups of patients with erysipelas of the lower extremities underwent indirect endolymphatic therapy with bicillin-3 (58 patients) and routine penicillin therapy (79 patients). Comparative clinicoimmunological examinations in the two groups revealed that lymphotropic administration of the antibi...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1417339

データ提供:米国国立医学図書館(NLM)

A Novel Approach to Erysipelas Treatment

The field of infectious disease research is constantly evolving, seeking new and effective ways to combat stubborn infections. This study delves into the realm of erysipelas, a bacterial skin infection, and investigates the potential benefits of indirect endolymphatic antibiotic therapy. This technique involves delivering the antibiotic directly to the lymphatic system, the body's intricate network of vessels that transport fluids and immune cells. The study compared this method to traditional intravenous penicillin therapy in two groups of patients with erysipelas of the lower extremities.

Lymphatic Targeting: A Potential Game Changer?

The researchers observed that the lymphotropic administration of bicillin-3, an antibiotic, led to a more favorable outcome for the patients. This was evidenced by a quicker resolution of the clinical signs of erysipelas, a lower incidence of early relapses, and a normalization of the majority of immunological parameters by the end of treatment. It appears that targeting the lymphatic system may be a more effective way to deliver antibiotics in certain types of infections.

The Importance of Precision in Treatment

The researchers also emphasize the need for a specific scale to assess the anti-recurrence efficacy of antibiotic therapy for erysipelas. This approach, based on the principles of Wald successive alternative analysis, aims to improve the accuracy and precision of treatment evaluations. Such a system could provide valuable insights into the long-term effectiveness of different treatment strategies for erysipelas.

Dr.Camel's Conclusion

This research paints a promising picture for the future of erysipelas treatment, suggesting that indirect endolymphatic antibiotic therapy may be a valuable tool in combating this infection. The potential benefits include faster healing times, lower relapse rates, and a more targeted delivery of medication. However, further research is necessary to fully understand the long-term implications of this approach and to refine the methodology for assessing its effectiveness.

Date :
  1. Date Completed 1992-11-17
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

1417339

DOI: Digital Object Identifier

1417339

SNS
PICO Info
in preparation
Languages

Russian

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