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Treatment of regional nodes.

Author: BelliF, CascinelliN

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The study discusses the treatment of melanoma that has spread to lymph nodes, which is associated with a poor prognosis. Surgery is the only proven treatment option for these patients, as chemotherapy and immunotherapy have not shown consistent effectiveness. While surgery is recommended for clinically involved lymph nodes, there is debate about the necessity of surgery for clinically uninvolved nodes. Studies on melanoma of the extremities have shown no difference in long-term outcomes for stage I melanoma patients, regardless of whether lymph node dissection is performed immediately or delayed. While there is less evidence for melanoma of the trunk, preliminary results and anatomical considerations suggest a similar surgical approach for these patients. The study concludes that, aside from specific cases, lymph node dissection should be considered only for patients with clinically involved regional lymph nodes.
Paper Details　
Original Abstract of the Article :
The appearance of nodal metastases from cutaneous melanoma represents a poor prognosis. Surgery is the only possible treatment for these patients since chemotherapy or immunotherapy have no confirmed specific efficacy in adjuvant or therapeutic schedules. If, for clinically metastatic regional nodes...See full text at original site
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引用元：
https://doi.org/10.1002/ssu.2980080607

データ提供：米国国立医学図書館（NLM）

Navigating the Treatment of Nodal Metastases: A Surgical Approach

The field of [oncology] is constantly seeking effective treatments for [nodal metastases], a significant challenge in managing [melanoma]. This research examines the role of [surgery] in treating [nodal metastases] from [cutaneous melanoma], exploring the current consensus and controversies surrounding this critical aspect of [melanoma] management.

Surgical Intervention: A Key Strategy in Melanoma Management

The study underscores the importance of [surgery] as the primary treatment option for [nodal metastases] from [cutaneous melanoma], highlighting the limited effectiveness of other modalities, such as [chemotherapy] and [immunotherapy]. The research emphasizes the need for a tailored approach to [node dissection], considering the specific characteristics of the [melanoma] and the patient's individual circumstances. While [node dissection] is considered the standard of care for [clinically involved regional nodes], the decision-making process for [clinically uninvolved nodes] remains a subject of ongoing debate.

Improving Outcomes: Understanding the Risks and Benefits

This research highlights the importance of careful consideration when deciding whether to perform [node dissection] in patients with [melanoma]. The study emphasizes the need for a thorough evaluation of the [melanoma], the patient's overall health, and the potential risks and benefits of [node dissection]. It's crucial to engage in a collaborative discussion with a qualified oncologist to determine the most appropriate treatment plan for each individual patient.

Dr.Camel's Conclusion

The desert of [melanoma] can be a challenging landscape, with [nodal metastases] presenting a formidable obstacle. This research provides valuable insights into the role of [surgery] in managing [nodal metastases], emphasizing the importance of a personalized approach and careful consideration of the risks and benefits of [node dissection]. It underscores the need for a multidisciplinary team to guide patients through this complex journey.

Date :
  1. Date Completed 1992-12-18
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1439447

DOI: Digital Object Identifier

10.1002/ssu.2980080607

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Article Analysis
・Effective treatment of melanoma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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