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Treatment of cutaneous squamous cell carcinomas by intralesional interferon alfa-2b therapy.

Author: BermanB, EdwardsL, EyreS P, GreenwayH T, PeetsE, RapiniR P, TannerD J, TaylorE L, TyringS, WhitingD A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Intralesional recombinant interferon alfa-2b was effective in treating actinically induced, primary cutaneous squamous cell carcinomas in 36 patients.
Paper Details　
Original Abstract of the Article :
Intralesional recombinant interferon alfa-2b has been shown to be effective in the treatment of actinic keratoses and basal cell carcinomas. This open-label study was designed to evaluate the effectiveness and cosmetic result of this therapy on actinically induced, primary cutaneous squamous cell ca...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1444502

データ提供：米国国立医学図書館（NLM）

Interferon Alfa-2b: A New Weapon in the Fight Against Squamous Cell Carcinoma

This study investigates the effectiveness of intralesional interferon alfa-2b therapy for the treatment of cutaneous squamous cell carcinomas (SCC). The researchers treated 36 SCC lesions with interferon alfa-2b, injected intralesionally three times per week for three weeks. Eighteen weeks after therapy, the treatment sites were excised and examined for remaining tumor. The study found that intralesional interferon alfa-2b therapy was effective in treating both invasive and in situ SCC lesions.

A New Hope for Squamous Cell Carcinoma

The study suggests that interferon alfa-2b therapy could be a valuable option for treating SCC. Think of a desert oasis, where life flourishes even in harsh conditions. Similarly, interferon alfa-2b therapy can provide a therapeutic oasis, offering a targeted approach to combatting SCC. The study's findings show the potential of this therapy to effectively treat both early and more advanced forms of the disease.

A Promising Approach to Skin Cancer Treatment

This study provides valuable information about the effectiveness of intralesional interferon alfa-2b therapy for SCC. It offers a promising new approach to skin cancer treatment, potentially leading to better outcomes for patients. As research continues to explore the potential of this therapy, we may see it become a more widely used treatment option for SCC. It’s a reminder that even in the face of seemingly insurmountable challenges, like skin cancer, researchers are continually finding new ways to fight the disease and improve the lives of affected individuals.

Dr.Camel's Conclusion

This study reminds us that even in the vast and often challenging landscape of cancer research, there are moments of hope and progress. The development of interferon alfa-2b therapy represents a step forward in the fight against SCC. It’s a testament to the dedication of researchers who are constantly seeking new ways to improve patient care and offer hope in the face of challenging diseases.

Date :
  1. Date Completed 1992-12-04
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

1444502

DOI: Digital Object Identifier

1444502

Related Literature

Article Analysis
・Side Effects of interferon alfa-2b injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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