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Present and future pharmacotherapy for osteoporosis.

Author: DoggrellSheila A

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study reviewed the various agents used in the treatment of osteoporosis, including calcium, vitamin D, estrogens, raloxifene, calcitonin, bisphosphonates, teriparatide, and other promising agents. The study highlights the different mechanisms of action of these agents, including bone resorption inhibition, bone formation stimulation, and other targets under development.
Paper Details　
Original Abstract of the Article :
Although neither calcium nor vitamin D has been shown to prevent osteoporosis in postmenopausal women alone, the combination does. Both calcium and vitamin D are commonly used in the treatment of osteoporosis. The estrogens and raloxifene both prevent bone loss in postmenopausal women, and the estro...See full text at original site
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引用元：
https://doi.org/10.1358/dot.2003.39.8.799409

データ提供：米国国立医学図書館（NLM）

Present and Future Pharmacotherapy for Osteoporosis

This comprehensive review provides an in-depth analysis of current and emerging pharmacotherapeutic approaches for osteoporosis. The study delves into the mechanisms of action, efficacy, and safety of various medications used to prevent and treat bone loss, highlighting the complex interplay of bone resorption and formation. It explores the role of calcium and vitamin D, estrogen and raloxifene, calcitonin, bisphosphonates (alendronate, risedronate, zoledronate), teriparatide, and other promising agents in the treatment of osteoporosis. Additionally, the study discusses the potential of new targets and drugs for future therapeutic interventions, including the OPG/RANKL/RANK system, cathepsin K inhibitors, and statins.

A Multifaceted Approach to Bone Health

This research underscores the importance of a multifaceted approach to managing osteoporosis. It highlights the various mechanisms of action of different medications, emphasizing the need for personalized treatment plans tailored to individual patient needs. The review also emphasizes the importance of ongoing research to develop new and more effective therapies for osteoporosis.

The Importance of Early Intervention for Bone Health

This review emphasizes the importance of early intervention for osteoporosis. It highlights the potential benefits of preventive measures, such as maintaining adequate calcium and vitamin D intake, engaging in regular physical activity, and addressing modifiable risk factors. Early diagnosis and treatment can significantly reduce the risk of fractures and improve quality of life for individuals with osteoporosis.

Dr.Camel's Conclusion

This review, like a camel navigating a vast and intricate desert of bone biology, provides a comprehensive overview of current and future pharmacotherapeutic approaches for osteoporosis. The study's findings offer valuable insights for healthcare providers and individuals seeking to optimize bone health and prevent fractures. This research serves as a beacon of hope for those seeking to combat osteoporosis and improve their quality of life.

Date :
  1. Date Completed 2004-02-06
  2. Date Revised 2019-11-08
Further Info :

Pubmed ID

14566385

DOI: Digital Object Identifier

10.1358/dot.2003.39.8.799409

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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