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The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903].
Author: GagnierJoel, JuurlinkDavid, MillsEdward, MontoriVictor M, ProuskyJonathan, RachlisBeth, RaskinGannady
Original Abstract of the Article :
BACKGROUND: Niacin is widely available over the counter (OTC). We sought to determine the safety of 500 mg immediate release niacin, when healthy individuals use them as directed. METHODS: 51 female and 17 male healthy volunteers (mean age 27 years SD 4.4) participated in a randomized placebo-contr...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280687/
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of OTC Niacin: A Cautionary Tale
[Niacin], a vitamin commonly available over-the-counter (OTC), is often touted for its potential health benefits. However, this randomized placebo-controlled trial explores the safety of a single dose of OTC niacin in healthy individuals. The researchers aimed to assess the incidence of flushing and other adverse effects associated with niacin use.
The Hidden Dangers of the Desert: Niacin's Side Effects Revealed
The findings of this study are like stumbling upon a hidden pit in the desert, revealing the potential risks associated with niacin use. The researchers found that niacin caused a high incidence of flushing, chills, pruritus, gastrointestinal upset, and cutaneous tingling in participants. These findings highlight the importance of caution when using niacin, particularly for individuals with pre-existing health conditions, much like a wise traveler navigating a dangerous desert landscape.
A Desert of Potential Complications: Understanding the Risks of Niacin
This study serves as a reminder that even seemingly innocuous medications can have potential side effects, much like a desert oasis that can appear inviting but harbor hidden dangers. The researchers emphasize the importance of consulting with a healthcare professional before using niacin, particularly in individuals with pre-existing health conditions, to ensure safe and effective treatment.
Dr. Camel's Conclusion
This study, like a warning sign in the desert, highlights the potential risks of niacin use. The findings suggest that caution is necessary when using OTC niacin, as it can cause significant side effects. Remember, while niacin may offer potential benefits, it's crucial to be aware of the risks and to consult with a healthcare professional to ensure safe and effective treatment.
Date :
- Date Completed 2005-03-16
- Date Revised 2018-11-13
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English
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