Lessons from 10 years of interferon beta-1b (Betaferon/Betaseron) treatment.

Author: BayasAntonios, GoldRalf

Paper Details 
Original Abstract of the Article :
In 1993, interferon beta-1b (IFN beta-1b, Betaferon/Betaseron) was the first interferon approved in the USA for relapsing-remitting multiple sclerosis (RRMS). Since then, dose-dependent effects of IFN beta in MS have been extensively discussed. Such effects had already been observed in the pivotal t...See full text at original site
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引用元:
https://doi.org/10.1007/s00415-003-1402-8

データ提供:米国国立医学図書館(NLM)

Interferon Beta-1b: A Decade of Lessons in Multiple Sclerosis Treatment

Multiple sclerosis (MS) research is an ever-evolving desert, filled with intricate pathways and challenges. This study delves into the long-term impact of interferon beta-1b (IFN beta-1b), the first interferon approved for relapsing-remitting MS (RRMS) in the United States back in 1993. Researchers used extensive analysis to investigate the effects of IFN beta-1b, considering both its dose-dependent effects and its effectiveness in secondary progressive MS (SPMS). The researchers found that IFN beta-1b has shown promise in managing RRMS and SPMS, especially in patients with active disease. The study also highlighted the importance of managing side effects, particularly flu-like symptoms and injection-site reactions, to ensure patient compliance.

Interferon Beta-1b Shows Promise for RRMS and SPMS

This study reveals that IFN beta-1b, a key player in MS treatment, offers significant benefits to patients with both RRMS and SPMS. The findings highlight the dose-dependent nature of IFN beta-1b, which underscores the importance of tailoring treatment to individual needs. For patients with SPMS, IFN beta-1b appears most effective in those with ongoing disease activity, including relapses or clear progression.

Managing Side Effects is Key to Successful Treatment

While IFN beta-1b provides a beacon of hope for MS patients, it's important to note that it can cause side effects. The study found that the most common side effects, particularly in the early stages of treatment, are flu-like symptoms and injection-site reactions. Managing these side effects effectively is crucial for ensuring patient compliance and maximizing the benefits of this therapeutic intervention.

Dr.Camel's Conclusion

IFN beta-1b has emerged as a crucial tool in the desert of MS treatment. This study illuminates the importance of long-term observation to understand the true effects of medications, as well as the delicate balance between efficacy and side effects. It reminds us that treating MS is a journey, not a destination. As researchers continue to explore new pathways, we'll gain a deeper understanding of how to best navigate this challenging terrain. Remember, knowledge is our compass in this vast and complex landscape.
Date :
  1. Date Completed 2004-03-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

14712395

DOI: Digital Object Identifier

10.1007/s00415-003-1402-8

Related Literature

SNS
PICO Info
in preparation
Languages

English

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