Paper Details

  1. Home
  2. Paper Details

Photodynamic therapy of multiple nonmelanoma skin cancers with verteporfin and red light-emitting diodes: two-year results evaluating tumor response and cosmetic outcomes.

Author: BissonnetteRobert, ChanAgnes, ElmetsCraig, HamzaviIltefat, HobbsLori, JainHem, LeePeter K, LuiHarvey, McLeanDavid, NeyndorffHerma, ProvostNathalie, SuXiang Yao, TopeWhitney D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Verteporfin photodynamic therapy demonstrated treatment benefit for patients with multiple nonmelanoma skin cancers. A single course resulted in histopathologic response rates ranging from 69% to 93%, with clinical complete response rates ranging from 51% to 95% at 24 months.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Efficient treatment of patients with multiple synchronous nonmelanoma skin cancers represents a therapeutic challenge. OBJECTIVE: To study the safety and efficacy of photodynamic therapy (PDT) with verteporfin and red light in the treatment of multiple nonmelanoma skin cancers. DESIGN:...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/14732656

データ提供：米国国立医学図書館（NLM）

Photodynamic Therapy for Multiple Nonmelanoma Skin Cancers: A New Hope for Treatment

Nonmelanoma skin cancers are a prevalent and potentially serious health concern. This study explores the efficacy and safety of photodynamic therapy (PDT) using verteporfin and red light-emitting diodes in treating patients with multiple synchronous nonmelanoma skin cancers. The researchers aimed to determine if PDT could provide a safe and effective treatment option for this challenging condition.

Verteporfin PDT for Multiple Skin Cancers: A Promising New Approach

The study demonstrated promising results. The histopathologic response rate ranged from 69% at 60 J/cm(2) to 93% at 180 J/cm(2), indicating the potential for PDT to effectively eliminate cancerous cells. The study also found that PDT was well-tolerated, with most adverse events being mild and localized to the treated areas. The researchers concluded that a single course of verteporfin PDT showed treatment benefit for patients with multiple nonmelanoma skin cancers.

A New Era in Skin Cancer Treatment: PDT Offers Hope for a Brighter Future

This research represents a significant step forward in the treatment of nonmelanoma skin cancers. PDT offers a potentially effective and safe alternative to traditional therapies, providing hope for patients seeking a more effective and less invasive treatment option. Just as a desert oasis provides relief from the harsh sun, PDT can offer relief from the burden of skin cancer.

Dr. Camel's Conclusion

This research, like a beacon of hope shining through the desert, offers a new approach to treating multiple nonmelanoma skin cancers. The study demonstrates that PDT, like a cool breeze on a scorching day, can provide relief and a chance for recovery. This promising therapy is a testament to the tireless efforts of researchers seeking to improve the lives of patients battling skin cancer.

Date :
  1. Date Completed 2004-02-05
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

14732656

DOI: Digital Object Identifier

140/1/26

Related Literature

Article Analysis
・Effective treatment of skin cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.