Paper Details

  1. Home
  2. Paper Details

Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac.

Author: AndersonAngela C, BrousseauDavid C, DuffySusan J, LinakisJames G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study found that intravenous prochlorperazine was more effective than intravenous ketorolac in treating pediatric migraine headaches. 84.8% of children who received prochlorperazine experienced a 50% or greater reduction in pain within 60 minutes, compared to 55.2% of those who received ketorolac. Both treatments were well tolerated, with only 2 children reporting mild and self-limited side effects.
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVE: We compare the effectiveness of intravenous ketorolac and intravenous prochlorperazine in the treatment of pediatric migraine headaches. METHODS: We performed a prospective, randomized, double-blind clinical trial in 2 pediatric emergency departments (EDs) within children's hospita...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/14747817

データ提供：米国国立医学図書館（NLM）

Treating Pediatric Migraines: A Race Against Time

Migraines are a formidable foe, causing intense pain and disruption to everyday life, especially for children. This study explores the effectiveness of two intravenous medications, prochlorperazine and ketorolac, in treating pediatric migraines. The study, conducted in a double-blind fashion, involved a race against time to alleviate the suffering of young patients. The results, like a refreshing desert breeze, offer valuable insights into the best approach for treating these debilitating headaches.

Prochlorperazine: A Strong Contender

The study found that prochlorperazine was significantly more effective than ketorolac in reducing migraine pain within 60 minutes. This discovery is like finding a hidden oasis in the midst of a desert storm, offering relief from the pain of migraines.

Finding the Right Oasis for Migraines

This research provides valuable guidance for treating pediatric migraines. The study's findings, like a signpost in the desert, point towards prochlorperazine as a more effective treatment option for children. Remember, in the vast desert of medical treatments, finding the right solution can make all the difference.

Dr. Camel's Conclusion

This research is a testament to the importance of finding the right treatment for every patient. The study's findings are a beacon of hope for children suffering from migraines, offering a more effective and faster-acting treatment option.

Date :
  1. Date Completed 2004-09-03
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

14747817

DOI: Digital Object Identifier

S0196064403007169

Related Literature

Article Analysis
・Side Effects of prochlorperazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.