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Effects of epoprostenol on right ventricular hypertrophy and dilatation in pulmonary hypertension.
Author: BoonstraAnco, BronzwaerJean G F, MarcusJ Tim, MarquesKoen M J, PostmusPieter E, RoeleveldRoald J, Vonk-NoordegraafAnton
Original Abstract of the Article :
OBJECTIVES: To gain more knowledge of changes in main pulmonary artery flow and right ventricular mass and volumes in patients with pulmonary hypertension during epoprostenol therapy. METHODS: Eleven patients (9 women) were evaluated before the start of therapy and every 4 months thereafter. Right ...See full text at original site
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引用元:
https://doi.org/10.1378/chest.125.2.572
データ提供:米国国立医学図書館(NLM)
Investigating Epoprostenol's Effects on Pulmonary Hypertension
Pulmonary hypertension, a serious condition affecting the heart and lungs, presents a significant challenge in the field of [cardiology]. This research investigated the effects of [epoprostenol], a medication commonly used to treat this condition, on [right ventricular hypertrophy and dilatation] in patients with [pulmonary hypertension]. The study employed [cine MRI] to measure [right and left ventricular volumes and masses] and [flow] in these patients. The findings indicate that [epoprostenol] reduces [pulmonary vascular resistance] leading to an increase in [pulmonary artery flow]. This improvement in [pulmonary artery flow] correlates with a better [6-min walking distance], a key indicator of exercise capacity in these patients. However, while [epoprostenol] improves [pulmonary artery flow], it does not reverse [right ventricular dilatation and hypertrophy], but it prevents further progression of these conditions.
Understanding the Impact of Epoprostenol on Pulmonary Hypertension
The study suggests that [epoprostenol] can effectively improve [pulmonary artery flow] in patients with [pulmonary hypertension] leading to improved exercise capacity. However, it's crucial to understand that [epoprostenol] does not fully reverse the structural changes associated with [pulmonary hypertension]. This research highlights the need for further investigations to explore potential treatments that can address the underlying structural changes in patients with this condition.
Living with Pulmonary Hypertension
This study underscores the importance of understanding the complexities of [pulmonary hypertension]. While [epoprostenol] offers a valuable tool for managing the condition, it's crucial to acknowledge that it does not provide a cure. However, the findings suggest that [epoprostenol] can significantly improve the quality of life for patients with [pulmonary hypertension] by increasing their exercise capacity and overall well-being. This research serves as a reminder of the ongoing quest for better treatments and ultimately, a cure for this debilitating condition.
Dr.Camel's Conclusion
The study demonstrates the beneficial effects of [epoprostenol] in improving [pulmonary artery flow] and exercise capacity in patients with [pulmonary hypertension]. While it does not reverse the structural changes associated with the condition, [epoprostenol] offers a valuable tool for managing [pulmonary hypertension] and improving the quality of life for those affected by this condition.
Date :
- Date Completed 2004-03-11
- Date Revised 2019-05-14
Further Info :
Related Literature
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