Cutaneous vasculitis secondary to ramipril.

Author: FergusonJ, GandhiN M, GuptaS

Paper Details 
Original Abstract of the Article :
A 61-year-old patient who had been treated with lisinopril in the past without any problems was commenced on ramipril for left ventricular dysfunction. He developed a painful symmetrical purpuric eruption over both feet after three days. A full vasculitis screen was negative. Ramipril was stopped an...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14964753

データ提供:米国国立医学図書館(NLM)

ACE Inhibitor-Induced Cutaneous Vasculitis: A Case Report

The field of [pharmacovigilance] is crucial in ensuring the safety and effectiveness of medications. This case report highlights the potential for ramipril, an angiotensin-converting enzyme (ACE) inhibitor, to induce cutaneous vasculitis, a rare but serious adverse reaction. The study describes the case of a 61-year-old patient who developed a painful purpuric eruption after starting treatment with ramipril. The findings underscore the importance of considering ACE inhibitor-induced cutaneous vasculitis in the differential diagnosis of skin rashes, particularly in patients with a history of intolerance to other ACE inhibitors.

ACE Inhibitors: A Potential Cause of Cutaneous Vasculitis

The case report serves as a reminder that even commonly prescribed medications like ACE inhibitors can have unexpected side effects. While cutaneous vasculitis is a rare complication, it can be serious and require prompt intervention. The study highlights the importance of being vigilant about potential adverse reactions to medications, even in patients who have previously tolerated similar drugs. Healthcare professionals should be aware of this rare but potentially serious complication, and patients should be encouraged to report any unusual skin changes or other symptoms while taking ACE inhibitors.

Navigating the Potential Risks of ACE Inhibitors

ACE inhibitors are widely used for managing hypertension and other cardiovascular conditions. While they offer significant benefits, it is crucial to be aware of potential adverse reactions like cutaneous vasculitis. Patients taking ACE inhibitors should be informed about the potential for this complication and encouraged to report any unusual skin changes or other symptoms promptly. Just as a camel needs to be vigilant for predators and obstacles in the desert, healthcare professionals and patients must be mindful of potential risks associated with medications.

Dr.Camel's Conclusion

This case report underscores the importance of vigilance in monitoring potential adverse reactions to medications. While ACE inhibitors are generally safe and effective, it is crucial to remain alert to potential side effects. Just as a camel must adapt to the ever-changing conditions of the desert, healthcare professionals and patients need to remain adaptable and informed when navigating the complexities of medication use.

Date :
  1. Date Completed 2004-04-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

14964753

DOI: Digital Object Identifier

14964753

Related Literature

SNS
PICO Info
in preparation
Languages

English

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