Lopinavir/ritonavir vs. indinavir/ritonavir in antiretroviral naive HIV-infected patients: immunovirological outcome and side effects.

Author: AdorniFulvio, BiniTeresa, BongiovanniMarco, ChiesaElisabetta, CicconiPaola, Monforte d'ArminioAntonella

Paper Details 
Original Abstract of the Article :
We compared immunovirological outcomes and toxicities of HAART regimens including LPV/r and IDV/r in antiretroviral naïve HIV-1 patients. We retrospectively selected 55 patients starting LPV/r and 52 starting IDV/r as first-line HAART. Immunovirological and metabolic parameters were recorded at base...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15026202

データ提供:米国国立医学図書館(NLM)

HIV Treatment: Navigating the Desert of Antiretroviral Regimens

The fight against HIV/AIDS has made significant strides, with effective antiretroviral therapies now available. However, choosing the right regimen for each patient can be a complex challenge. This research explores the effectiveness and side effects of two antiretroviral regimens – lopinavir/ritonavir (LPV/r) and indinavir/ritonavir (IDV/r) – in HIV-infected patients who have never received antiretroviral treatment before.

Comparing Antiretroviral Regimens: A Tale of Two Regimens

The researchers compared the effectiveness and toxicity of LPV/r and IDV/r regimens in a group of HIV-infected patients. They found that both regimens successfully suppressed viral load but that IDV/r was associated with a lower probability of virological success and a higher risk of discontinuation due to side effects.

The Importance of Personalized Treatment in HIV Care

This research emphasizes the need for individualized treatment decisions when it comes to HIV. Like a desert traveler choosing the right path, healthcare providers must carefully weigh the benefits and risks of each regimen to find the best option for each patient.

Dr.Camel's Conclusion

This study highlights the importance of carefully considering the effectiveness and side effects of different antiretroviral regimens in HIV-infected patients. Personalized treatment strategies are crucial for optimizing treatment outcomes and minimizing the risk of adverse effects.

Date :
  1. Date Completed 2004-07-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15026202

DOI: Digital Object Identifier

S0166354203002985

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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