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Lopinavir/ritonavir vs. indinavir/ritonavir in antiretroviral naive HIV-infected patients: immunovirological outcome and side effects.
Author: AdorniFulvio, BiniTeresa, BongiovanniMarco, ChiesaElisabetta, CicconiPaola, Monforte d'ArminioAntonella
Original Abstract of the Article :
We compared immunovirological outcomes and toxicities of HAART regimens including LPV/r and IDV/r in antiretroviral naïve HIV-1 patients. We retrospectively selected 55 patients starting LPV/r and 52 starting IDV/r as first-line HAART. Immunovirological and metabolic parameters were recorded at base...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/15026202
データ提供:米国国立医学図書館(NLM)
HIV Treatment: Navigating the Desert of Antiretroviral Regimens
The fight against HIV/AIDS has made significant strides, with effective antiretroviral therapies now available. However, choosing the right regimen for each patient can be a complex challenge. This research explores the effectiveness and side effects of two antiretroviral regimens – lopinavir/ritonavir (LPV/r) and indinavir/ritonavir (IDV/r) – in HIV-infected patients who have never received antiretroviral treatment before.
Comparing Antiretroviral Regimens: A Tale of Two Regimens
The researchers compared the effectiveness and toxicity of LPV/r and IDV/r regimens in a group of HIV-infected patients. They found that both regimens successfully suppressed viral load but that IDV/r was associated with a lower probability of virological success and a higher risk of discontinuation due to side effects.
The Importance of Personalized Treatment in HIV Care
This research emphasizes the need for individualized treatment decisions when it comes to HIV. Like a desert traveler choosing the right path, healthcare providers must carefully weigh the benefits and risks of each regimen to find the best option for each patient.
Dr.Camel's Conclusion
This study highlights the importance of carefully considering the effectiveness and side effects of different antiretroviral regimens in HIV-infected patients. Personalized treatment strategies are crucial for optimizing treatment outcomes and minimizing the risk of adverse effects.
Date :
- Date Completed 2004-07-20
- Date Revised 2013-11-21
Further Info :
Related Literature
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