Common and rare side-effects of low-dose thalidomide in multiple myeloma: focus on the dose-minimizing peripheral neuropathy.

Author: BrunoriMarino, CandelaMarco, CapelliDebora, CatariniMassimo, CorvattaLaura, LeoniPietro, MalerbaLara, MarconiMonica, MeleAnna, MontanariMauro, OffidaniMassimo, OlivieriAttilio, RupoliSerena

Paper Details 
Original Abstract of the Article :
Thalidomide has demonstrated a remarkable efficacy in the treatment of multiple myeloma but its use may cause several toxicities. We have investigated the common and rare side-effects, especially analysing peripheral neuropathy, in order to optimise the thalidomide dose for minimizing this harmful s...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15128418

データ提供:米国国立医学図書館(NLM)

Thalidomide: A Double-Edged Sword in Multiple Myeloma

This study delves into the [oncology] realm, examining the complex relationship between thalidomide, a potent drug used in the treatment of multiple myeloma, and its potential side effects. The researchers focused on optimizing thalidomide dosage to minimize the risk of [peripheral neuropathy], a debilitating side effect that can significantly impact quality of life. By investigating the common and rare side effects associated with thalidomide, the study aims to pave the way for safer and more effective treatment strategies for multiple myeloma patients.

Balancing Efficacy and Safety: A Delicate Dance

The study highlights the importance of carefully managing thalidomide dosage to maximize its therapeutic benefits while minimizing the risk of adverse effects. Although thalidomide has demonstrated remarkable efficacy in treating multiple myeloma, its potential for causing peripheral neuropathy demands careful consideration. The researchers' insights could lead to personalized treatment strategies tailored to each patient's risk profile and therapeutic needs.

Navigating Thalidomide Therapy: A Balancing Act

The delicate balance between the benefits and risks of thalidomide therapy is a key consideration for individuals battling multiple myeloma. Just as the desert camel navigates the treacherous sand dunes, we must carefully navigate the complexities of this powerful drug. Open communication with your healthcare provider is crucial to ensure you receive the most appropriate treatment plan and to minimize potential side effects. Understanding the potential risks and benefits of thalidomide therapy empowers you to make informed decisions about your treatment journey.

Dr. Camel's Conclusion

Navigating the desert of multiple myeloma treatment requires careful planning and a keen eye for the nuances of each therapeutic option. Thalidomide, while a valuable weapon in the fight against this cancer, must be wielded with precision to avoid the perils of peripheral neuropathy. Just as the desert camel navigates the shifting sands with cautious steps, we too must carefully consider the potential risks and benefits of each therapeutic approach.

Date :
  1. Date Completed 2004-06-15
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15128418

DOI: Digital Object Identifier

EJH238

Related Literature

SNS
PICO Info
in preparation
Languages

English

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