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Safety of Diastat, a rectal gel formulation of diazepam for acute seizure treatment.

Author: PellockJohn M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Diazepam rectal gel (Diastat) is a medication used to treat seizures in patients with epilepsy. This study reviewed the safety of Diastat, finding it to be a safe and effective treatment option.
Paper Details　
Original Abstract of the Article :
Diazepam rectal gel (Diastat) is the only medication approved by the US FDA for the management of selected, refractory patients with epilepsy, on stable regimens of antiepilepsy drugs, who require intermittent use of diazepam to control bouts of increased seizure activity. An analysis of the safety ...See full text at original site
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引用元：
https://doi.org/10.2165/00002018-200427060-00003

データ提供：米国国立医学図書館（NLM）

Diastat: A Safe and Effective Rescue Medication for Seizures

This analysis examines the safety and efficacy of diazepam rectal gel (Diastat), a medication approved for managing refractory epilepsy. The authors compare the safety profile of Diastat to that of intravenous diazepam, highlighting its advantages in terms of respiratory depression, abuse potential, and suitability for out-of-hospital use. Their analysis underscores the importance of Diastat as a safe and effective rescue medication for individuals with epilepsy.

Diastat: A Safe and Effective Rescue Medication for Seizures

The analysis suggests that Diastat is a safe and effective rescue medication for individuals with epilepsy, offering several advantages over intravenous diazepam. The rectal gel formulation minimizes the risk of respiratory depression and abuse, making it a suitable option for out-of-hospital use by caregivers. The analysis emphasizes the importance of Diastat as a valuable tool for managing refractory seizures and improving the quality of life for individuals with epilepsy.

Improving Seizure Management and Patient Safety

This analysis underscores the importance of developing safe and effective rescue medications for individuals with epilepsy. Diastat provides a valuable tool for managing refractory seizures, offering a convenient and safe alternative to intravenous diazepam. The analysis highlights the commitment to improving patient safety and quality of life through the development of innovative and effective treatment options.

Dr.Camel's Conclusion

Living with epilepsy can be a challenging journey, much like traversing a desert landscape filled with unpredictable hazards. Diastat offers a valuable lifeline for individuals facing this challenge, providing a safe and effective rescue medication that can empower them to manage seizures and live more fulfilling lives. It’s a reminder that even in the face of adversity, there’s always a path towards improving health and well-being.
Date :
  1. Date Completed 2004-07-26
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

15144232

DOI: Digital Object Identifier

10.2165/00002018-200427060-00003

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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