Oral isotretinoin in the treatment of recalcitrant condylomata acuminata of the cervix: a randomised placebo controlled trial.

Author: BoziE, GeorgalaC, GeorgalaS, KatoulisA C, MortakisA

Paper Details 
Original Abstract of the Article :
BACKGROUND: Conventional therapies for human papillomavirus (HPV) infection are often associated with unsatisfactory response rates and high recurrence rates. The use of a systemic agent may more effectively control the virus. OBJECTIVES: To investigate the efficacy and safety of low dose oral isot...See full text at original site
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引用元:
https://doi.org/10.1136/sti.2003.006841

データ提供:米国国立医学図書館(NLM)

Treating Stubborn Cervical Warts: A Look at Oral Isotretinoin

The field of [HPV infection treatment] has long grappled with the challenge of [recalcitrant condylomata acuminata (RCA)]. Conventional therapies often fall short, leaving patients with [unsatisfactory response rates and high recurrence rates]. This research sought to uncover whether [low dose oral isotretinoin] could offer a more effective solution. The authors conducted a [double blind placebo controlled clinical trial] involving [60 women] with [RCA of the cervix] who had not responded to at least one conventional therapy. Their findings reveal that [oral isotretinoin] demonstrated [considerable efficacy], leading to [complete response] in a significant portion of participants. Notably, [only one complete responder experienced recurrence during the 12 month follow up] highlighting the potential for [long-lasting treatment effects].

A Promising Treatment Option for Cervical Warts

These results suggest that [oral isotretinoin] may hold promise as a safe and effective alternative for treating [RCA of the cervix]. The statistically significant difference between the treatment and placebo groups points to the efficacy of this approach. The low recurrence rate adds another layer of appeal to this potential treatment option.

A New Hope for a Stubborn Condition

For those struggling with [RCA], this research offers a glimmer of hope. The study suggests that [oral isotretinoin] could be a valuable tool for managing this often stubborn condition. However, as with any medical intervention, it's crucial to consult with a healthcare professional to determine the most appropriate treatment plan.

Dr. Camel's Conclusion

This research offers a beacon of hope for individuals facing the challenge of [recalcitrant cervical warts]. Oral isotretinoin shines as a potential treatment option with significant efficacy and a low recurrence rate. Just like my camel caravan navigates the treacherous sands of the desert, this research paves the way towards a more effective approach to managing this condition.

Date :
  1. Date Completed 2004-07-12
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

15170007

DOI: Digital Object Identifier

10.1136/sti.2003.006841

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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