A randomized controlled trial to compare calcipotriol with betamethasone valerate for the treatment of cutaneous lichen planus.

Author: , GohChee Leok, MachinDavid, SureshShirley, TanSuat Hoon, ThengColin Thiam Seng, WongHwee Bee

Paper Details 
Original Abstract of the Article :
BACKGROUND: Topical calcipotriol is a vitamin D3 analogue which influences keratinocyte proliferation and differentiation. Its efficacy in cutaneous lichen planus has not been well evaluated. METHODS: This is a randomized open-label trial comparing the effectiveness of calcipotriol 50 microg/g vers...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15204145

データ提供:米国国立医学図書館(NLM)

Calcipotriol vs. Betamethasone for Lichen Planus

This research compares the efficacy of two topical treatments for cutaneous lichen planus: calcipotriol and betamethasone valerate. The study, a randomized open-label trial, aimed to evaluate the effectiveness of these treatments in reducing lesion thickness, pigmentation, and pruritus, and promoting lesion clearance. The study found that both calcipotriol and betamethasone valerate showed similar effectiveness in treating cutaneous lichen planus. While both treatments resulted in a gradual improvement in lesion thickness, pigmentation, and pruritus, there was little difference in the overall clinical response between the two groups. This research provides insights into the comparative effectiveness of calcipotriol and betamethasone valerate for cutaneous lichen planus, suggesting that both treatments may be equally effective in managing this condition.

Topical Treatments for Lichen Planus: A Comparative View

This study offers a comparison of two commonly used topical treatments for cutaneous lichen planus: calcipotriol and betamethasone valerate. The research demonstrates that both treatments can be effective in managing this condition, although no significant differences in efficacy were observed between the two groups. The study emphasizes the importance of carefully considering patient-specific factors and treatment preferences when choosing a topical treatment for cutaneous lichen planus.

Finding Relief from Lichen Planus: A Collaborative Approach

This research highlights the need for a collaborative approach to managing cutaneous lichen planus. While both calcipotriol and betamethasone valerate showed similar effectiveness, it's important to work closely with a dermatologist to determine the best treatment approach for each individual. Just as a camel navigates the desert by carefully choosing its path, patients with cutaneous lichen planus need to work with their healthcare providers to find the most effective and appropriate treatment plan for their specific needs.

Dr. Camel's Conclusion

This study is a valuable reminder that the journey of managing cutaneous lichen planus can sometimes feel like navigating a desert landscape. The research suggests that both calcipotriol and betamethasone valerate can be effective options, but finding the right path may require some exploration and collaboration with a dermatologist. Just as a camel relies on its instincts and knowledge of the desert to find its way, patients need to trust their healthcare providers and actively participate in their treatment journey.
Date :
  1. Date Completed 2004-08-05
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

15204145

DOI: Digital Object Identifier

FYUYXYVNK86TBDXH

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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